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Orange peels may hold a key to better cardiovascular health, new University of Florida-led research shows.

Heart disease is the leading cause of death for men, women and people of most racial and ethnic groups, according to the Centers for Disease Control and Prevention.

Recent research has shown that some gut bacteria help develop cardiovascular disease. When they feed on certain nutrients during digestion, gut bacteria produce trimethylamine N-oxide (TMAO). Levels of TMAO can help predict future cardiovascular disease, according to researchers at the Cleveland Clinic.

With help from a $500,000 USDA grant, Yu Wang and her team investigated the potential of orange peel extracts – rich in beneficial phytochemicals – to reduce TMAO and trimethylamine (TMA) production. Scientists tested two types of extracts: a polar fraction and a non-polar fraction.

To get the polar fractions, scientists used polar and non-polar solvents to extract the orange peel, Wang said.

“If you imagine your salad dressing, anything in the water or vinegar part are the polar fraction; anything in the oil away from water is the non-polar fraction,” Wang said. “The solvents we used were not exactly like water and oil, but they possess similar polarity.”

Results from the study showed that the orange peel non-polar fraction extract effectively inhibited the production of harmful chemicals. Researchers also identified a compound called feruloylputrescine in the orange peel polar fraction extract that also significantly inhibits the enzyme responsible for TMA production.

“This is a novel finding that highlights the previously unrecognised health potential of feruloylputrescine in reducing the risk of cardiovascular disease,” said Wang, a UF/IFAS associate professor of food science and human nutrition.

The orange peel finding is significant because 5 million tons of orange peels are produced each year in orange juice production nationwide. Nearly 95 % of Florida oranges are used for juice. About half of the peels go to feed cattle. The rest goes to waste.

But the Food and Drug Administration considers natural orange peel extracts safe for human consumption. So, Wang hope to put the peels to better use.

“These findings suggest that orange peels, often discarded as waste in the citrus industry, can be repurposed into valuable health-promoting ingredients, such as diet supplements or food ingredients,” said Wang, a faculty member at the UF/IFAS Citrus Research and Education Center. “Our research paves the way for developing functional foods enriched with these bioactive compounds, providing new therapeutic strategies for heart health.”

About UF/IFAS
The mission of the University of Florida Institute of Food and Agricultural Sciences (UF/IFAS) is to develop knowledge relevant to agricultural, human and natural resources and to make that knowledge available to sustain and enhance the quality of human life. With more than a dozen research facilities, 67 county Extension offices, and award-winning students and faculty in the UF College of Agricultural and Life Sciences, UF/IFAS brings science-based solutions to the state’s agricultural and natural resources industries, and all Florida residents.

Scientists in Germany have discovered a new ‘super’ apple juice which has the potential to improve heart health by boosting blood flow1.

Researchers at Hochschule Geisenheim University, near Frankfurt, have found a way to maximise polyphenols in apple juice by using a novel squeezing method called a spiral filter press which actively takes out oxygen by vacuum-driven pressing. Moreover, they ensured that oxygen is excluded from all other processing steps, therefore reducing nutrient deterioration.

The new study, published in Food Research International, found that this new method boosted polyphenol content by four times as much as regular apple juice. Polyphenols are natural plant compounds found in fruit, red wine, and cocoa which are known to have a range of health benefits for the heart and brain.

A 280 ml serving of the new apple juice would be enough to provide 100 % of the ideal intake for a key group of polyphenols, called flavan-3-ols, which help promote a healthy blood flow. The ideal intake of 400 – 600 milligrams per day for cardiovascular health was proposed by an international consortium of scientists in 20222.

The British Heart Foundation estimates that there are 7.6m people living in the UK with heart or circulatory diseases3. Meanwhile, data from the 2021 census show that 32 % of adults suffered from high blood pressure (hypertension) and 3 in 10 of those (29 %) were undiagnosed; equating to approximately 4.2 million adults with undiagnosed hypertension4.

Lead author of the paper, Professor Ralf Schweiggert, commented: “Apple juice is already a source of polyphenol compounds, but you would need to drink several glasses to reach the levels recommended by scientists for heart health effects. The new juicing method that we’ve investigated takes the polyphenol content to a new level by minimising the nutrient losses we typically see during juicing.”

Co-Researcher of the study, Stefan Dussling, said: “Nutrient losses are commonly due to the presence of oxygen which quickly degrades some of the nutrients in apple juice like flavan-3-ols or vitamin C. This would happen when we juice apples at home or buy a ready-made product. We hope that the new juicing method will be used more widely in the future to help people get more of these beneficial natural compounds simply by drinking one glass of juice”.

1Dussling S et al. (2024) Analytical characterization of flavan-3-ol-rich apple juices produced with the innovative spiral filter press technology. Food Research International 180 (2024): 114055.
2Crowe-White K et al. (2022) Flavan-3-ols and Cardiometabolic Health: First Ever Dietary Bioactive Guideline. Adv Nutr 13(6):2070-2083.
3https://www.bhf.org.uk/-/media/files/for-professionals/research/heart-statistics/bhf-cvd-statistics-uk-factsheet.pdf
4https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/healthandwellbeing/

Abstract

The health effects of 100 % fruit and vegetable juices (FVJ) represent a controversial topic. FVJ contain notable amounts of free sugars, but also vitamins, minerals, and secondary compounds with proven biological activities like (poly)phenols and carotenoids. The review aimed to shed light on the potential impact of 100 % FVJ on human subject health, comprehensively assessing the role each type of juice may have in specific health outcomes for a particular target population, as reported in dietary interventions. The effects of a wide range of FVJ (orange, grapefruit, mandarin, lemon, apple, white, red, and Concord grapes, pomegranate, cranberry, chokeberry, blueberry, other minor berries, sweet and tart cherry, plum, tomato, carrot, beetroot, and watermelon, among others) were evaluated on a series of outcomes (anthropometric parameters, body composition, blood pressure and vascular function, lipid profile, glucose homeostasis, biomarkers of inflammation and oxidative stress, cognitive function, exercise performance, gut microbiota composition and bacterial infections), providing a thorough picture of the contribution of each FVJ to a health outcome. Some juices demonstrated their ability to exert potential preventive effects on some outcomes while others on other health outcomes, emphasising how the differential composition in bioactive compounds defines juice effects. Research gaps and future prospects were discussed. Although 100 % FVJ appear to have beneficial effects on some cardiometabolic health outcomes, cognition and exercise performance, or neutral effects on anthropometric parameters and body composition, further efforts are needed to better understand the impact of 100 % FVJ on human subject health.

Please download the Open Access article under: www.cambridge.org

(Source: Cambridge University)

Public-private partnership to advance citrus research, development of breakthrough solutions for food, beverage and fragrance industries

In a ceremonial presentation, IFF and Florida Polytechnic University laid the foundation for the new Citrus Innovation Center, located on the University’s campus in Lakeland, Florida. The nearly 30,000-square-foot, standalone building will support global citrus research and development, and will include sensory and experience venues, research labs, processing, analytical departments, a fully equipped citrus garden and amenities for hosting customers and partners.

“What an honour to celebrate this beacon for innovation and excellence, that is a perfect blend of science and creativity,” said Nicolas Mirzayantz, president, Nourish Division, IFF. “As we lay the foundation for a global citrus innovation center, we re-affirm IFF’s commitment to invest in R&D capabilities that unlock the development of innovative solutions for our customers, partners and communities we operate in. This facility represents a significant milestone in our cross-divisional citrus strategy. Here, we will accelerate innovation by combining the expertise from our Nourish and Scent divisions with on-campus talent who are just as committed to pushing the boundaries of science and uplifting the citrus industry as a whole.”

Nestled on the university’s campus in the heart of the citrus belt, the new, best-in-class center for excellence is designed, engineered and constructed by Ryan Companies, who upon completion, will maintain the building. The sprawling, glass-fronted building and surrounding grounds are slated for completion in late 2023.

“IFF holds a leading position in R&D investment,” said Christophe de Villeplée, president, Scent Division, IFF. “This cutting-edge facility represents one more way we’re combining creativity and science, working closely with our partners and customers. Citrus extracts are an essential component of our creations, bringing consumers delightful freshness. By building a transformational, holistic citrus development ecosystem in one of the world’s central citrus locations, we will further deepen our knowledge, and facilitate the creation of differentiated citrus products that delight global food, beverage and fragrance customers, while doing more good for people and planet.”

IFF will be the first company located on Florida Poly’s campus. The company anticipates providing hands-on internships and job opportunities for Florida Poly students in areas of research and development, customer experience, supply and operational coordination and entrepreneurship. Additionally, IFF will support the University through funding and collaborating on faculty research, sponsoring senior capstone projects, and supporting academic programs.

“We are proud that IFF recognised the strategic advantage in partnering with our University,” said Randy K. Avent, president of Florida Poly. “Our students and faculty are making real contributions in growing the tech industry by influencing the designs of pioneering technologies and real-world solutions. We’re excited about the cross-disciplinary learning opportunities for our students through this partnership in fields such as metabolomics, automation, artificial intelligence, virtual and augmented reality, and biometric data capture and analysis, to name a few.”

The building capitalises on views toward the campus, overlooking the expansive ponds and the campus front entry. Its architectural design draws inspiration from the building’s purpose: the exterior reflects the density and discernment of aromas, scents and taste sensations, showcasing acute moments of knowledge, research and gathering, and the flow of those experiences between spaces.

“The ethereal nature of the design concept was challenging, however Ryan was able to successfully create a dynamic, unique architectural expression that reflects the nature of the work being done within the facility, while complementing the existing architecture on the campus,” said Linaea Floden, regional director of Architecture for Ryan A+E.

Research from Swansea University has found how plastics commonly found in food packaging can be recycled to create new materials like wires for electricity – and could help to reduce the amount of plastic waste in the future.

While a small proportion of the hundreds of types of plastics can be recycled by conventional technology, researchers found that there are other things that can be done to reuse plastics after they’ve served their original purpose.

The research, published in The Journal for Carbon Research, focuses on chemical recycling which uses the constituent elements of the plastic to make new materials.

While all plastics are made of carbon, hydrogen and sometimes oxygen, the amounts and arrangements of these three elements make each plastic unique. As plastics are very pure and highly refined chemicals, they can be broken down into these elements and then bonded in different arrangements to make high value materials such as carbon nanotubes.

Research shows black plastics could create renewable energy
Conversion of plastics to carbon nanotube materials (Foto: Swansea University)

Dr Alvin Orbaek White, a Sêr Cymru II Fellow at the Energy Safety Research Institute (ESRI) at Swansea University said: “Carbon nanotubes are tiny molecules with incredible physical properties. The structure of a carbon nanotube looks a piece of chicken wire wrapped into a cylinder and when carbon is arranged like this it can conduct both heat and electricity. These two different forms of energy are each very important to control and use in the right quantities, depending on your needs.

“Nanotubes can be used to make a huge range of things, such as conductive films for touchscreen displays, flexible electronics fabrics that create energy, antennas for 5G networks while NASA has used them to prevent electric shocks on the Juno spacecraft.”

During the study, the research team tested plastics, in particular black plastics, which are commonly used as packaging for ready meals and fruit and vegetables in supermarkets, but can’t be easily recycled. They removed the carbon and then constructed nanotube molecules from the bottom up using the carbon atoms and used the nanotubes to transmit electricity to a light bulb in a small demonstrator model.

The research team plan to make high purity carbon electrical cables using waste plastic materials and to improve the nanotube material’s electrical performance and increase the output, so they are ready for large-scale deployment in the next three years.

Dr Orbaek White said: “The research is significant as carbon nanotubes can be used to solve the problem of electricity cables overheating and failing, which is responsible for about 8 % of electricity is lost in transmission and distribution globally.

“This may not seem like much, but it is low because electricity cables are short, which means that power stations have to be close to the location where electricity is used, otherwise the energy is lost in transmission.

“Many long range cables, which are made of metals, can’t operate at full capacity because they would overheat and melt. This presents a real problem for a renewable energy future using wind or solar, because the best sites are far from where people live.”

The U.S. Department of Agriculture’s National Institute of Food and Agriculture has awarded $1.8 million to two Cornell food science research projects.

One project improves the commercial viability of a new food packaging material that actively reduces the need for preservatives, while decreasing food waste; the other project improves juice and beverage production to keep the fresh taste in concentrates.

Ever-increasing food waste represents an emerging threat to the economic and environmental sustainability of the U.S. food system, said Julie M. Goddard, associate professor of food science. Preservatives are added to foods to retain quality with a longer shelf life, but consumers are demanding a reduction in additives.

However, this consumer movement leads to unintended results: food that spoils more quickly, which could cause a surge in food waste.

“We’ve shown that you can introduce preservative functionality into packaging materials, so that we can reduce the additives in foods and beverages without losing product quality,” Goddard said. These “active packaging” materials are a promising new technology, but technological hurdles and consumer-mindsets have so far prevented their successful commercial translation, she added.

Removing the preservatives in food products – such as sauces, mayonnaise or salad dressing – would severely diminish shelf life, even with refrigeration. But by adding chelating agents – compounds that can sequester metal ions – to the jar or bottle itself, the food can last much longer without the additives seeping into the food.

“There is a lot of benefit in having fewer additives but gaining the preservative quality built-in to the package so they don’t migrate to the food,” she said.

During the research phase, the researchers will work directly with consumers and producers to ensure that the packaging material meets food-production, supply chain needs and that consumers are more likely to accept this new technology.

Joining Goddard on this project will be co-principal investigators Randy Worobo, professor of food science, and Motoko Mukai, assistant professor of food science; David Just, professor of applied economics at the Charles H. Dyson School of Applied Economics and Management; and Chris Ober, professor of materials science and engineering.

For the other project, Carmen Moraru and Olga Padilla-Zakour, both professors of food science, will lead research on using reverse and forward osmosis filtration and other cold processes to create nutritious, high-quality and tasty juices and beverages in an energy-efficient way. Collaborators include Miguel Gomez, associate professor of applied economics at Dyson, and Robin Dando, associate professor of food science.

Currently, juice processors use heat to create juice concentrate, but heat changes the product’s nutritional and sensory profiles.

“Our combination nonthermal process maintains product quality and makes the juice concentrate taste like it is fresh,” Moraru said.

Also, juice concentration consumes energy. “With this cold process technology, we can save energy and conduct the concentration at a fraction of the thermal evaporation cost,” she said.

The researchers will examine different filtration conditions for specific juices and other beverages. In addition to New York state fruit juices like apple and grape juice, the researchers will also examine concentration of cold-brew coffee and tea.

Juice and beverage concentrates make sense from a financial perspective, Moraru said.

“For commercial purposes,” she said, “it is more economical to transport concentrate rather than move the added weight of water. Concentrate is economical and stable, while water makes juices more prone to degradation.”

The developed processes will be transferred to industry stakeholders. Said Moraru: “Ultimately, this work will benefit consumers and will help boost the competitiveness and sustainability of the U.S. food sector by reducing the energy in food processing.”

These new projects add to the department’s growing research output in improving environmental sustainability in the U.S. and global food production by reducing food waste while improving energy efficiency.