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Study found that a combination of a probiotic and prebiotic—referred to as a “synbiotic”—can significantly reduce heart muscle damage caused by diet-induced cardiac disease

In a new peer reviewed study published in the Journal of the American College of Cardiology: Basic to Translational Science, Irish researchers have discovered novel links between gut microbes, inflammation and heart disease. Additionally, the study demonstrated that giving a single probiotic combined with a soluble dietary fibre protects against heart disease. The study used Tate & Lyle’s PROMITOR® Soluble Corn Fibre as the prebiotic component.

The study shows the profound impact of the gut-heart connection on cardiac health. For the first time, a human scale model revealed the full extent of the “gut-heart axis,” showing how gut microbe imbalance and inflammation originating in the gut can contribute to heart damage. Excitingly, the study found that a combination of a probiotic and prebiotic – referred to as a “synbiotic” – can significantly reduce heart muscle damage caused by diet-induced cardiac disease.

This research, led by scientists from APC Microbiome Ireland (APC), a world-leading Research Ireland centre based at University College Cork (UCC), and Teagasc (the Irish Agriculture and Food Development Authority), was conducted in collaboration with Tate & Lyle, a world leader in ingredient solutions for healthier and tastier food and beverages. The findings demonstrate the potential of reducing the risk of heart disease – especially in people with poor diets and obesity, half of whom experience cardiovascular issues – by manipulating the gut microbiome with synbiotics.

“This is the first time that a bacteria residing only in the gut has successfully been used to treat heart disease associated with obesity and high blood pressure, and our synbiotic treatment equals some of the best available cardiac drugs in a human scale model. This work opens new avenues for potentially groundbreaking disease-modifying therapy in patients with obesity, high blood pressure and diet-related heart disease,” said Prof. Noel Caplice, an APC Principal Investigator, Chair of Cardiovascular Sciences at UCC, and Consultant Cardiologist at Cork University Hospital.

Prof. Catherine Stanton, Senior Principal Research Officer at Teagasc Moorepark Food Research Centre and an APC Principal Investigator, emphasised the innovative potential of this work: “This study highlights the critical role the gut microbiome plays in our health and physiology. Our results are a testament to the power of harnessing gut microbes to protect against some chronic diseases like heart failure. It’s an exciting step forward in personalised nutrition.”

Dr Kavita Karnik, Global Head of Nutrition, Regulatory and Scientific Affairs at Tate & Lyle praised the innovative work, commenting: “At Tate & Lyle, we are proud to support and partner in cutting-edge research that explores how our dietary fibres, when combined with probiotic strains, can be used to improve health outcomes. It is exciting to see the integral role played by PROMITOR® Soluble Corn Fibre in this unique symbiotic combination. This work creates new opportunities to leverage our science and ingredients to have a positive impact on significant public health challenges such as obesity and associated cardiometabolic outcomes.”

The paper, ‘Targeting the Gut-Heart Axis Improves Cardiac Remodelling in a Clinical Scale Model of Cardiometabolic Syndrome’, is available to read online here.

  • The festive period is the most popular time for couples to conceive according to the Office for National Statistics1
  • As the seasonal baby boom begins, nine out of ten women will have marginal or low levels of folate – a vital nutrient which protects the foetus2
  • According to the NHS, expectant mothers can need up to 10 times more folate during pregnancy than the average adult to help their baby develop normally3
  • Dietitian, Dr Frankie Phillips, shares three simple but effective dietary tips for expectant mothers to boost their folate levels

Research by the University of Southampton has highlighted a concerning trend: nine out of ten women will have marginal or low levels of folate and other vital nutrients around the time of conception.2

Folate, also known as vitamin B9, can be found in a range of food and drinks and is essential during pregnancy to prevent neural tube defects, like spina bifida. The average adult needs 200 micrograms of folate a day, but pregnant women need at least double this dose due to the demands of pregnancy. According to the NHS, some expectant mothers can even require up to 10 times the average adult recommendation.3

This common deficiency can extend into late pregnancy, potentially impacting the health of both mother and child. According to healthcare professionals, symptoms of a folate deficiency can include fatigue, pins and needles, mouth ulcers, and a sore red tongue.2

A developing baby needs folate to make healthy new cells, and to make genetic materials (DNA and RNA). Deficiency in the early stages of pregnancy can harm the neural tube which protects the spinal cord – affecting more than 1000 pregnancies a year in the UK. More generally, the health benefits of folate include encouraging the production of red blood cells in bone marrow, which is vital during periods of growth and development such as pregnancy, infancy and adolescence.

As the winter months herald the season of festive celebrations, they also mark the beginning of the most popular time of year for conception, evidenced by September’s leading birth rates.1 Dr Frankie Phillips, a registered dietitian with over 20 years’ experience, highlights the importance of optimal nutrition during family planning and pregnancy.

Dr Frankie Phillips comments: “Folate is needed for many important processes in the body, including helping form healthy red blood cell and contributing to the reduction of tiredness and fatigue.A 150ml glass of 100 % orange juice is a recognised source of folate and a convenient, affordable way to help achieve daily nutrient requirements.”

For women who think they may be suffering with low folate levels, Dr Phillips recommends a few simple but effective ways to incorporate more folate into your diet.

Three steps to incorporate folate-rich food and drinks into your diet:

  • Drink a daily glass of 100% Orange Juice: Whether you buy a bottle from the shop or crank up the juicer at home, pure orange juice is a great source of folate and provides essential minerals like potassium, magnesium, and iron, according to a new Spanish study.4 Just one glass of orange juice a day is a recognised source of folate.
  • Include Leafy Greens: Incorporate folate-rich leafy greens such as spinach, kale, and broccoli into your diet to support foetal development and overall health. Try adding a handful of spinach to stews or curries and stir-frying broccoli stems with lean beef and soy sauce.
  • Add Legumes to Meals: Include peas, lentils, chickpeas, and beans in your diet, as they are excellent sources of folate. For example, just one cup of cooked lentils contains 90 % of the daily recommendation. Legumes are also rich in protein, fibre and antioxidants.5

Researchers, Dr Montana Camara and Dr Laura Dominguez, who recently published a study on the vitamin and mineral content of orange juice, noted: ” Folate is an essential mineral supporting foetal development by helping to release energy from the mother’s diet, and promoting normal development of the nervous system, especially during conception and pregnancy.”

Their study found that packaged fruit juices were a good source of folate, potassium and vitamin C.

1https://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/livebirths/bulletins/birthcharacteristicsinenglandandwales/2022
2https://www.southampton.ac.uk/news/2023/12/pregnant-women-missing-vital-nutrients-needed-for-them-and-their-babies.page
3https://www.nhs.uk/medicines/folic-acid/common-questions-about-folic-acid/ ; https://www.nhs.uk/pregnancy/keeping-well/vitamins-supplements-and-nutrition/#:~:text=But%20when%20you’re%20pregnant,you’re%2012%20weeks%20pregnant
4Cámara, M., Domínguez, L., Medina, S.; Mena, P., García-Viguera,C. A Comparative Analysis of Folate and Mineral Contents in Freshly Squeezed and Commercial 100% Orange Juices Available in Europe.Nutrients 2024, 16, 3605. https://doi.org/10.3390/nu1621360
5https://fdc.nal.usda.gov/food-search?query=&type=Foundation

Good value for money more important than low price – and organic is back

The complexity of world affairs has not lessened since March 2023. World crises have not gone away, rather the opposite. One positive development is that the inflation rate dropped in Europe1. This change is also reflected in the survey by Südzucker regarding consumers’ price sensitivity. If the price sensitivity is decreasing, other aspects of purchase criteria must gain importance in comparison. But what are the growing interests of consumers when buying food & beverages?

Main purchase criteria – naturlness, organic and regionality gain focus

The top three drivers for purchasing food & beverages did not change: taste, health and price. But while taste and price dropped significantly, health remained stable. Aspects like naturalness, organic and regionality, however, are continuing to grow in importance.

Taste as the number one purchase decision remained on a high level and far above from the second important driver – health. The drop may indicate that taste is more and more of a given for the consumer and a must-have. The fact that a good taste and sensory profile is a matter of course is also evident when it comes to sugar-reduced products.

Taste as the number one purchase decision remained on a high level and far above from the second important driver – health. The drop may indicate that taste is more and more of a given for the consumer and a must-have. The fact that a good taste and sensory profile is a matter of course is also evident when it comes to sugar-reduced products. 60 % (incl. Italy) are concerned about how sugar reduction in food/drinks is achieved. In comparison to price, taste went down in Belgium and the UK, while price fell significantly in all countries. One potential reason for consumers‘ decreasing price sensitivity could be explained by the decreasing inflation rate in Europe1; consumers no longer look for the cheapest product, but for the product with the best value for money that also fulfils other consumer needs. It must be clear to consumers what they are getting for their money

Please download the full Südzucker Consumer Study 2024 for free under www.suedzucker.com.

1Source: Eurostat – Annual inflation down to 2.45 in the euro area (europa.eu)

New study explores the impact of EU Sustainability Regulations and the implications of the new EU Deforestation Regulation (EUDR) for global commodity supply chains and consumer markets

  • EUDR aims to cut greenhouse gas emissions and help limit biodiversity loss by influencing global action on climate change targeting commodities linked to deforestation
  • EUDR will require companies trading in certain commodities who wish to trade with the EU to prove that their product and its value chain are deforestation-free
  • EUDR compliance premiums for companies operating in the supply chain for oil palm products and their derivatives and rubber could be in excess of USD 1.5 billion for these two commodities alone. This could lead to price increases as companies are likely to pass on the extra costs of EUDR compliance to consumers
  • Food, drink and personal care categories likely to be most affected by retail price hikes due to the EUDR include coffee, chocolate, soy-based meat alternatives and oil palm products and their derivatives including hundreds of personal care products such as shampoo

The EU Deforestation Regulation (EUDR), which comes into force at the end of the year, is the latest round of EU sustainability regulation which attempts to influence global regulatory policy and value-chain practices as part of the bloc’s effort to achieve key aims of The European Green Deal such as no net emissions of greenhouse gases by 2050.

The EUDR is arguably one of the most far reaching and impactful pieces of EU sustainability regulation, targeting commodities linked to deforestation, which includes cattle, cocoa, coffee, oil palm, rubber, soya, and wood as well as some of their derived products, such as paper/paperboard, leather, shampoo, chocolate, tyres, and furniture.

EUDR Compliance

Under the EUDR companies that trade in these commodities and their derived products in the EU market or who export them from the EU will need to follow mandatory due diligence reporting of the goods and supply chains they wish to trade in and demonstrate that their products are not linked to deforestation, or to forest degradation through, for example, the expansion of agricultural land. The regulation will require companies and industries in countries that supply the EU to transition to a sustainable, deforestation-free supply chain and legal agricultural value chain if they wish to trade in the EU.

USD 1.5 billion potential cost to EU consumers

Agribusiness Consultants at GlobalData a leading data and analytics company estimate that EUDR compliance premiums for companies operating in the supply chain for just two of the targeted commodities, oil palm products and their derivatives (such as crude palm oil (CPO) and palm kernel oil (KPO)), and rubber could be in excess of *USD 1.5 billion alone. Whilst companies operating in these supply chains will be able to absorb some of the costs themselves a good proportion of these compliance premiums are likely to be passed onto EU consumers in the form of food and drinks and product price increases.

EU Sustainability Regulations study

GlobalData Food & Beverages Consultants’ new study: ‘EU Sustainability Regulations: How the EUDR and other Sustainability Regulations will impact consumer markets’, explores some of the EUs key sustainability regulations focusing on the aims of the EUDR and the compliance challenges ahead for farmers, companies, and manufacturers trading in the commodities targeted by the regulation.

The study also looks at what the EUDR could mean for the global supply chain of the target commodities, the potential impact on consumer markets and pricing within the EU and how the EUDR could affect the bloc’s future competitiveness with China.

With the EUDR coming into full force on 30th December 2024 for large companies (2025 for SME’s), the new study is also a timely reminder for large companies operating in the Food & Beverages, Foodservice, Retail and Packaging sectors to finalise their EUDR compliance strategy over the next six months to avoid being late in aligning their operations with the new EUDR rules.

It could be argued that the EU aims to use the ‘Brussels effect’ to direct global policy on sustainability. This is the idea that the global landscape responds to the EU ‘externalizing’ its laws because the bloc is such a significant global consumer market. According to **Eurostat, the EU has a population of over 448.7 million people, one of the biggest consumer markets in the world.

The European Investment Bank predicts that the EUs various climate actions could result in a potential hit to EU-wide GDP of – 0.4 % by 2030, taking into account all of the EUs sustainability initiatives, but says the costs of not acting would be greater.

Fred Diamond Senior Food & Beverages Consultant and Analyst at GlobalData comments: “The aims of the EUDR are understandable and cutting greenhouse gas emissions and protecting biodiversity is essential. However, there could be some disruption ahead. The extra demands of the EUDR could lead some commodity suppliers in what the EU terms ‘third countries’ to move away from the EU and increase trade with countries that impose fewer regulatory requirements such as China. Some food categories, such as plant-based meat, may have to reformulate and switch to other protein sources, such as pea protein if the result of the EUDR is an increase in the price of soya for food production.

“The gap between big and small companies could get wider as larger companies are more able to shoulder the additional regulatory burden. The exact impact on consumers will depend on a variety of factors, including how companies choose to respond to the regulation, the extent to which the regulation is enforced, and how much assistance EU member states are willing to give to supplier countries to help them align with the new rules. However, with recent news reports confirming that the world’s top climate scientists expect global heating to go well beyond the current 1.5C target, sustainability regulation associated with cutting greenhouse gas emissions, such as the EUDR which targets deforestation, remains an urgent priority for the planet.”

To read GlobalData Food & Beverages Consultant’s new study ‘EU Sustainability Regulations: How the EUDR and other Sustainability Regulations will impact consumer markets’ in full please download your free copy here

*The USD 1.5 billion EUDR compliance premium figure is based on GlobalData Agribusiness consultants understanding of current commodity pricing and the likely impact of increased costs of EUDR compliance on the supply chain of these commodities. However, the company recognises that EUDR compliant commodity premiums are still being agreed confidentially between buyers and sellers so some uncertainty remains over the final numbers.
**Eurostat is the statistical office of the European Union.

  • A recent study reveals that natural sugars found in fruit juice appear to support physical recovery after exercise
  • Cloudy apple juice was found to recover the intestinal barrier function more quickly than other drinks – this helps to support recovery
  • The body’s stress makers reduced more quickly in recovery after drinking fruit juice when compared with other beverages
  • The study, led by Dr Patrick Diel, shines a light on the potential health benefits of fruit juice for fitness enthusiasts

Drinking fruit juice could help the body recover more quickly after intense physical activity such as long-distance running, according to a new study.

The peer-reviewed study, published in international journal, Nutrients, found that while added sugars can have a negative impact on the intestinal barrier after exercise, the naturally occurring sugars and polyphenols (plant compounds) found in fruit juice seem to support a more balanced recovery.

While it’s common to reach for a sugary sports drink during or after exercise, scientists have known for some time that added sugars can cause problems with the intestinal barrier – a critical part of our immune defence. A leaky intestinal barrier can lead to harmful bacteria crossing from the gut into the blood which stimulates inflammation. This, then, increases the risk of overtraining syndrome and metabolic conditions such as endotoxemia – where the body has a toxic reaction to bacteria.

The study, led by Dr Patrick Diel, was set up to find out whether fruit juices caused the same inflammatory effect as sugar-sweetened drinks.

The researchers looked at the gut health of runners before and after an ultramarathon. They compared the impact of drinking diluted cloudy apple juice with a test drink which mimicked a typical sugary sports drink. This contained identical amounts of sugar but not the polyphenols and other fruit complexes naturally found in juice.

The researchers found that, while both exercise and sugars can disrupt the intestinal barrier, the natural compounds found in fruit juice eased these effects*. Runners who drank the cloudy apple juice after the race recovered their intestinal barrier function more quickly than those who drank the sugar-sweetened test drink*.

Another part of the study on amateur runners found that drinking diluted cloudy apple juice after running influenced a protein called CD14 suggesting that the juice supported the body’s immune system. Furthermore, the study showed that runners who drank fruit juice reduced their stress markers more quickly compared with those who drank the sugar-sweetened test drink.

Dr Patrick Diel from German Sport University in Cologne, said: “The research comes at a timely moment for anyone inspired to get more active in the run up to the Olympic games, and these findings offer a fresh perspective how to best replenish our bodies. Simply diluting cloudy apple juice and drinking it after playing sports or exercising seems to be an easy and healthy option which supports both gut health and immune function”.

Award-winning dietitian, Dr Carrie Ruxton said: “To properly recover after exercise, our bodies need healthy carbohydrates. In light of these findings, I would encourage athletes, fitness enthusiasts and causal gym-goers to add a serving of around 150ml of cloudy apple juice to their sports bottle and top up with tap water for a low cost and effective sports drink. Not only will this mixture keep us hydrated, it also provides energy-giving natural sugars and polyphenols to promote optimal recovery.”

As with any dietary change, it is important to drink juice in moderation and as part of a balanced diet. However, these studies suggest that when it comes to supporting the body after an Olympic-inspired workout, cloudy apple juice is the perfect health hack.

*Valder, S. et al. Effect of Sugar- and Polyphenol-Rich, Diluted Cloudy Apple Juice on the Intestinal Barrier after Moderate Endurance Exercise and in Ultra-Marathon Runners. Nutrients 2024, 16, 1353. https://doi.org/10.3390/nu16091353

Orange peels may hold a key to better cardiovascular health, new University of Florida-led research shows.

Heart disease is the leading cause of death for men, women and people of most racial and ethnic groups, according to the Centers for Disease Control and Prevention.

Recent research has shown that some gut bacteria help develop cardiovascular disease. When they feed on certain nutrients during digestion, gut bacteria produce trimethylamine N-oxide (TMAO). Levels of TMAO can help predict future cardiovascular disease, according to researchers at the Cleveland Clinic.

With help from a $500,000 USDA grant, Yu Wang and her team investigated the potential of orange peel extracts – rich in beneficial phytochemicals – to reduce TMAO and trimethylamine (TMA) production. Scientists tested two types of extracts: a polar fraction and a non-polar fraction.

To get the polar fractions, scientists used polar and non-polar solvents to extract the orange peel, Wang said.

“If you imagine your salad dressing, anything in the water or vinegar part are the polar fraction; anything in the oil away from water is the non-polar fraction,” Wang said. “The solvents we used were not exactly like water and oil, but they possess similar polarity.”

Results from the study showed that the orange peel non-polar fraction extract effectively inhibited the production of harmful chemicals. Researchers also identified a compound called feruloylputrescine in the orange peel polar fraction extract that also significantly inhibits the enzyme responsible for TMA production.

“This is a novel finding that highlights the previously unrecognised health potential of feruloylputrescine in reducing the risk of cardiovascular disease,” said Wang, a UF/IFAS associate professor of food science and human nutrition.

The orange peel finding is significant because 5 million tons of orange peels are produced each year in orange juice production nationwide. Nearly 95 % of Florida oranges are used for juice. About half of the peels go to feed cattle. The rest goes to waste.

But the Food and Drug Administration considers natural orange peel extracts safe for human consumption. So, Wang hope to put the peels to better use.

“These findings suggest that orange peels, often discarded as waste in the citrus industry, can be repurposed into valuable health-promoting ingredients, such as diet supplements or food ingredients,” said Wang, a faculty member at the UF/IFAS Citrus Research and Education Center. “Our research paves the way for developing functional foods enriched with these bioactive compounds, providing new therapeutic strategies for heart health.”

About UF/IFAS
The mission of the University of Florida Institute of Food and Agricultural Sciences (UF/IFAS) is to develop knowledge relevant to agricultural, human and natural resources and to make that knowledge available to sustain and enhance the quality of human life. With more than a dozen research facilities, 67 county Extension offices, and award-winning students and faculty in the UF College of Agricultural and Life Sciences, UF/IFAS brings science-based solutions to the state’s agricultural and natural resources industries, and all Florida residents.

Research into ultra-processed foods (UPF) and their role in today’s diet is becoming an increased focus for healthcare professionals. But with a range of studies emerging and differing opinions on the matter, it can be confusing for consumers to navigate what the broad term really means.

A recent study highlighted some of these misconceptions when almost half of respondents (45 %) said they wouldn’t be able to define or identify an ultra-processed food or beverage, and the same amount said they don’t know the difference between ultra-processed and minimally processed products.

Orange juice was highlighted as one of the most common misconceptions amongst Brits in the study, with 21 % believing the drink was ultra-processed, despite being minimally processed. In the same study, 19 % even said they avoid buying orange juice as they worry it sits in the UPF category.

Award-winning nutritionist and health writer, Dr Emma Derbyshire says: ‘Some of the misunderstandings around ultra-processed foods are resulting in consumers avoiding certain products which contain healthy benefits. Products like 100 % orange juice are essential in a balanced diet and provide essential vitamins and minerals, such as Vitamin C and potassium, needed to help meet an individual’s nutrient needs.”

Top 5 orange juice truths:

  • Unlike ultra-processed products, 100 % orange juice contains no added sugars and cannot be diluted with water under European law
  • Fruit juice counts as one of your 5-a-day fruit and vegetables – a convenient and nutritious way to up your fruit intake
  • The high levels of vitamin C found naturally in fruit juice help the immune system to combat symptoms of common colds and illness and support normal skin health
  • Fruit juice contains potassium, which supports normal blood pressure
  • Drinking orange juice helps your body absorb iron from plant foods

According to a recent study conducted by Fact.MR, the global citrus fiber market reached a valuation of USD 317 million in 2022 and is projected to achieve USD 550 million by the conclusion of 2032. The market is anticipated to witness an expansion of demand opportunities at a Compound Annual Growth Rate (CAGR) of 5.6 % through the forecast period. A primary driver stimulating growth within the global citrus fibers market is the escalating demand for natural, plant-based ingredients in both food and personal care products.

The surge in demand for gluten-free and vegan products within the food and beverage sector is a significant contributor to the heightened sales of citrus fibers. As consumers increasingly become aware of the adverse health effects associated with the consumption of processed foods, there is a notable shift towards plant-derived ingredients, thereby fostering growth prospects within the citrus fibers market.

Citrus fibers are emerging as effective alternatives to sodium triphosphate, thereby augmenting their incorporation in processed meat products. This trend is further bolstering the market for citrus fibers, as manufacturers seek cleaner and more natural ingredients to meet consumer preferences and industry standards.

Furthermore, citrus fibers exhibit a high fat-binding capacity and are adept at stabilising emulsions, making them increasingly sought-after in the bakery and confectionery sectors. This growing utilisation of citrus fibers in such applications is expected to contribute favorably to the market’s growth trajectory in the foreseeable future.

Expanding beyond the realm of food and beverage, citrus fibers are gaining prominence in skincare and personal care products as well. With their rich vitamin C content, citrus fibers offer benefits such as improving skin tone, reducing dark spots, and addressing hyperpigmentation. These attributes have led to heightened interest in orange and lemon citrus fibers for incorporation into skincare products, consequently driving up their sales.

Leading players in the citrus fiber market include:

  • CEAMSA
  • Fiberstar, Inc.
  • CP Kelco, Inc.
  • Herbafoods Ingredients GmbH
  • Florida Food Products, Inc.
  • Golden Health

According to Fact.MR’s analysis, the demand for citrus fibers is poised to witness a notable uptick in the United States, fueled by the increasing adoption within the food and beverage as well as personal care industries. Moreover, the rising preference for vegan and plant-based products across the nation is expected to sustain and further boost the sales of citrus fibers in the years leading up to 2031.

Key takeaways from citrus fiber market analysis:

  • Based on applications, personal care segment is projected to grow at a 5 % CAGR, remaining a dominant area of application.
  • By function, citrus fibers as water binders & fat replacers will account for over 50 % of the total market share through 2031.
  • The U.S. is estimated to account for 9/10th of the total citrus fibers market sales, placing the country as a lucrative market.
  • Increasing popularity of gluten-free and plant-based ingredients in Brazil will augment market growth, holding over 40 % of the total market share by 2031.

“Surging cases of food-borne diseases due to artificial flavours and colours used in processed food will encourage adoption of natural citrus fibers. Considering this, sales of citrus fiber-based pharmaceuticals will increase, further augmenting growth in the market through 2031,” says the Fact.MRanalyst.

Growth drivers:

  • Growing awareness regarding negative health effects of synthetic flavouring in food products will favour adoption of citrus fibers.
  • Increasing significance of clean labels in food and personal care products will drive sales of citrus fibers.

Market segmentations:

  • by nature: organic, conventional
  • by grade: food-grade, pharma-grade, others
  • by source: oranges, tangerines/mandarians, grapefruit, lemons and limes
  • by function: gelling gums, thickening gums, water binders & fat replacers
  • by application: desserts and ice-creams, snacks and meals, bakery products, sauces and seasonings, meat & egg replacements, personal care, pharmaceuticals, beverages, flavourings, and coatings, others
  • by distribution channel: online channel, convenience stores, supermarkets and hypermarkets, department stores, specialty stores, pharmacies
  • by region: North America, Europe, Asia Pacific, Latin America, Middle East & Africa

Competitive landscape

Major citrus fiber suppliers are actively broadening their consumer reach to establish a dominant market presence in the foreseeable future. Employing arange of strategic approaches, these suppliers are pursuing growth opportunities within the market. These strategies encompass various tactics such as mergers, acquisitions, collaborations, expanding company footprints, forging partnerships, launching innovative products, and more.

Recent developments

  • Azelis, in July 2021, established a collaboration with CP Kelco to broaden its capabilities for distribution around the Netherlands for citrus fibers and some other natural food ingredients.
  • Fiberstar Inc., in 2019, launched a new website for citrus fiber Citi-Fi to showcase its products along with providing education to consumers around the world. The company is also taking initiatives to improve its digital experience.
  • Orange Fiber is a popular startup that has announced the launching of a novel fabric range made from pulp and citrus fiber with collaborations with Marinella brands and H&M.
  • CP Kelco is a leader that provides solutions in natural ingredients and has unveiled the launch of a novel innovation center for pilot plant scale-up and research applications.

These insights are based on a report on Citrus Fiber Market by Fact.MR.

New study finds that 100 % fruit juice:

  • Accounts for up to 26 % of children’s vitamin C intake, and up to 19 % in adults
  • Contributes up to 4 % of daily potassium, which supports normal blood pressure
  • Provides up to 7 % of daily intake of folate which supports a healthy pregnancy
  • Only contributes up to 14 % of free sugar in people’s daily diets, compared with up to 92% from products containing added sugar such as soft drinks, biscuits, sweets, chocolate and cakes
Fruit juice provides up to a quarter of Vitamin C intake, according to a new study
(Photo: Fruit Juice Science Centre)

Drinking 100 % fruit juice has a negligible impact on daily calories but accounts for up to a quarter of children’s vitamin C intake and is an important source of other vital nutrients, according to a new study1 which highlights the importance of juice in a healthy diet.

Because fruit juice contains natural sugar, some policy makers and researchers have expressed concern that it could lead to weight gain, if consumed regularly. But a new analysis of national dietary surveys across 14 European countries for which data were available, found that people who drink fruit juice consume on average just 137 g per day, lower than the recommended serving size of 150 – 200 ml2 that exists in some countries.

This equated to just 20 – 40kcal per day, or 1 – 2 % of a child’s or adult’s average daily energy intake, which would not be expected to have an impact on body weight.

In contrast, the average daily serving of 100 % fruit juice across each age group across Europe was enough to make a significant contribution to daily intakes of vitamin C, which is vital for immune function and boosts iron absorption.

The study, published in the journal, Nutrition Research Reviews, found that fruit juice was responsible for 4 – 20 % of daily vitamin C intake in infants, 6 – 26 % in children, 8 – 20 % in teenagers, 8 – 19 % in adults and 6 – 19 % in older adults.

The study’s lead author, Dr Janette Walton from Munster Technological University in Cork, said: “Fruit juice is a major contributor to vitamin C intakes in children and adults. Given that too few people eat the recommended 5-a-day of fruit and vegetables, fruit juice is a convenient and nutritious food in the diet”.

The researchers also found that fruit juice accounted for 2 – 4 % of daily potassium, which supports normal blood pressure and has been found to be lacking in people’s diets according to the European Food Safety Authority (EFSA), and 1 – 7 % of daily intake of folate which supports a healthy pregnancy and is commonly too low in the diets of most women of childbearing age.

Meanwhile, the natural sugar in 100 % fruit juice, which comes entirely from the fruit, contributed to just 2 – 14 % of free sugar in people’s daily diets, compared with 48 – 92 % which is estimated to come from “optional” products containing added sugar such as soft drinks, biscuits, sweets, chocolate and cakes.

Fruit juice provides up to a quarter of Vitamin C intake, according to a new study
(Photo: Fruit Juice Science Centre)

Unlike sodas, nectars or other drinks, 100 % fruit juice never contains added sugars and cannot be diluted with water under European law.

Dr Walton continued: “Our findings showed only a modest contribution of fruit juice to free sugars. In contrast, a recent review found that sweet foods and drinks with added sugars are the major sources of added sugars across Europe, contributing half to more than 90 % of intakes).

“This highlights the importance of targeting sugar reduction strategies for discretionary/’top-shelf’ foods which are not recommended in food-based dietary guidelines. Unlike fruit juice whose composition is controlled by law, these types of products can be legally reformulated to reduce their sugar content”.

More broadly, the authors of the study highlighted the lack of data on 100% fruit juice consumption in many countries in Europe, such as Germany, which they said makes it difficult to set Europe-wide policies without an accurate view of normal consumption levels.

1Walton J & Kehoe L (2024) Current perspectives and challenges in the estimation of fruit juice consumption across the lifecycle in Europe – PubMed (nih.gov)
2Equivalent to 150 – 200 g since 1 gram = 1 ml.

Tate & Lyle and Cryptobiotix’s breakthrough ex-vivo* study shows that sucralose does not impact the gut microbiota, while other low and no calorie sweeteners have potentially beneficial health effects

A new, first-of-its-kind study has identified unique and potentially beneficial interactions between certain low and no calorie sweeteners, including stevia, and the human gut microbiota. Tate & Lyle PLC, a world leader in ingredient solutions for healthier food and drink, partnered with Cryptobiotix, pioneers in preclinical gastrointestinal research, on the study.

Dr. Davide Risso, molecular biology specialist and Tate & Lyle’s Head of Nutrition Research, led the project to explore the potential impact of certain low and no calorie sweeteners on the gut environment in both healthy individuals and those with type 2 diabetes. The research involved taking samples from co-living adults consuming a similar diet – to lower the potential variation introduced by differences in long-term diet, a major driver of microbiota composition. The doses of low and no calorie sweeteners used were based on actual intakes, regulations and amounts that are generally included in foods and beverages during different timepoints.

Results from the pre-clinical study, published in the leading peer reviewed, open-access journal the International Journal of Food Sciences and Nutrition, found that some of the studied low calorie and no calorie sweeteners had no impact on the gut microbiota, while others had potential beneficial health effects.

Using Cryptobiotix’s cutting-edge SIFR® (“cipher”) technology to recreate the gut environment outside of the human body, the research partners found that sweeteners, such as sucralose, do not impact the microbial composition of the gut. Furthermore, other sweeteners, including stevia, have a beneficial impact on the gut microbiota as they were found to be easily fermented and increase the density of certain health-supporting bacteria, with the production of short-chain fatty acids.

The study adds to the strong scientific evidence demonstrating the beneficial role low and no calorie sweeteners can play when used as a part of a balanced diet. Assessments of additional low and no calorie sweeteners, including allulose and erythritol, are being completed and details will be shared in due course.

Dr. Davide Risso, Tate & Lyle’s Head of Nutrition Research, said:
“In this study, the low and no calorie sweeteners we have assessed are shown to have either no impact on the gut microbiota or to offer potential health benefits beyond their established sugar and calorie reduction benefits. Human clinical trials will be required to confirm the potential health benefits. At Tate & Lyle, we’re committed to advancing understanding around the role of low and no calorie sweeteners in the diet and sharing knowledge in this emerging field as a purpose-led, science-driven company.”

Dr Pieter Van den Abbeele, Cryptobiotix’s Chief Scientific Officer, said:
“Cryptobiotix was founded with the ambition of providing accurate insights into the impact and behaviour of ingredients in relation to the gut microbiome. This study provides much-needed evidence to consider the potential benefits of sweeteners individually, rather than as a uniform whole. The robustness and validation work that went into the SIFR® technology used, allowed us to pinpoint specific health-promoting pathways in relation to specific low and no calorie sweeteners.”

*In ex vivo studies, living tissues are directly taken from a living organism and studied in a laboratory with minimal alterations to the organism’s natural conditions.

A new study is claiming that there is a link between caffeine and substance use in adolescence.

In response to the research, BSDA Director General Gavin Partington said:

This study contains several significant limitations, as the authors themselves acknowledge. BSDA members do not market or promote energy drinks to under-16s, nor do they sample products with this age group. In addition, energy drinks carry an advisory note stating ‘not recommended for children’.

The BSDA Code of Practice on energy drinks was introduced by and for our members in 2010 and contains a number of stringent points on responsible marketing. We remain committed to supporting the responsible sale of energy drinks.

UCLA study highlights Smart Cups' revolutionary technology reducing environmental impact of liquid consumer products
More Delivered, Less Trucks Needed! Smart Cups’ efficient technology means fewer transportation vehicles needed with greater volume of products delivered. (Photo: Smart Cups)

Smart Cups, a pioneering sustainability-driven technology company behind innovative ingredient printing announced the publication of a new research study in the esteemed journal Resource, Conservation & Recycling. The study, titled “Reducing life cycle material, energy and emissions for liquid consumer products through printing,” conducted by UCLA’s Institute of the Environment and Sustainability and authored by Professor Deepak Rajagopal, has brought to light the remarkable potential of Smart Cups Technology in transforming the consumer-packaged goods industry and contributing to a greener future.

“The technology that Smart Cups has pioneered has the potential to drastically reduce the environmental burden of beverages and several other liquid products through a reduction in total packaging and transportation across the product lifecycle,” said Professor Deepak Rajagopal. “The implications of this research extend beyond the consumer-packaged goods industry. Major companies, including industry giants like Pepsi, Coke, and Proctor and Gamble, could benefit from Smart Cups’ ground-breaking approach to delivering products more sustainably. Embracing this innovation can help such large corporations achieve sustainability goals and become leaders in eco-friendly practices”.

The study focuses on the profound environmental benefits of Smart Cups Technology which enables direct printing of consumer product ingredients onto surfaces, leading to substantial reductions in packaging materials, energy consumption, carbon emissions and overall environmental burdens. The study unveils the far-reaching implications for not just the beverage industry, but also the consumer-packaged goods industry as whole, promising to revolutionise distribution logistics and minimise environmental impact.

Key highlights from the study include:

  • The study’s findings show that a single Class 6 or 7 beverage truck packed with Smart Cups can accommodate a staggering 21 times more beverage volume than PET bottles and 31 times than glass bottles.
  • Smart Cups printed on PLA cups, when paired with tap water, result in 20 % less packaging materials than aluminum, 40 % less than plastic, and an impressive 90 % less than glass-based packaging.
  • This reduction in packaging translates into a 23 % to 48 % decrease in lifecycle primary energy and a 40 % to 57 % decrease in global warming potential. With biogenic carbon credit for landfilled PLA, the reductions reach an impressive 50 % to 70 %.

Smart Cups Technology is the first of its kind, revolutionising the delivery of liquid consumer products and minimising their environmental impact. This research not only amplifies the positive impact Smart Cups Technology can have on the world but also strengthens the validation of its significant benefits by reshaping the consumer products industry. By eliminating the need for bulky packaging materials, such as PET bottles or glass containers, Smart Cups optimise beverage payload, allowing for substantially higher volumes to be transported within the same truck weight limits. This breakthrough not only enhances logistical efficiency but also reduces the carbon footprint associated with transportation, as fewer trucks are required to transport the same amount of beverage.

The implications of this research extend far beyond the immediate benefits of increased payload capacity. By revolutionizing beverage transportation, Smart Cups are poised to transform the entire industry landscape, introducing a new era of sustainability and efficiency. With the potential to streamline distribution networks and reduce reliance on fossil fuels, Smart Cups offer a visionary solution to the pressing environmental challenges faced by the beverage sector.

The UCLA study underscores the profound impact of Smart Cups on beverage transportation, highlighting the unparalleled payload capacity that this innovative packaging technology provides. As industry leaders and consumers alike seek more sustainable and efficient solutions, Smart Cups stands at the forefront of a transformative movement. The researchers at UCLA are confident that their findings will inspire further exploration and adoption of Smart Cups within the beverage industry, ultimately leading to a greener, more efficient future.

To access the full article and learn more about the study, please visit: https://www.sciencedirect.com/science/article/abs/pii/S0921344923001866?dgcid=author

According to the scientific study conducted by Professor Christian Fischer of the Free University of Bolzano, the company contributes to a 10% reduction in harvest losses in the apple sector.

An estimated 22 % of fruit and vegetables are lost every year during or immediately after harvest. Much of global food waste therefore occurs at the beginning of the value chain, long before products reach the market.

Through its activities, VOG Products contributes to reducing this phenomenon, thanks to its business model, to efficient planning and the significant technological investments made in recent years. The South Tyrolean producer organisation is one of the largest in the sector in Europe and processes about 70 – 80 % of the Italian industrial apple harvest (20 % of the Trentino-South Tyrol harvest).

The validity of the anti-waste model adopted by VOG Products is demonstrated by a recent scientific study conducted by Christian Fischer, Professor of Agricultural and Food Economics at the Free University of Bolzano, which was also presented at the 2022 International Horticultural Congress in Angers (France).

In the study, titled “The apple processing cooperative VOG Products as a role model for minimising post-harvest crop losses – an empirical case study from South Tyrol, Italy”, Professor Fischer demonstrates how VOG Products significantly contributes to reducing harvest and post-harvest losses in the apple production chain. While internationally apple wastage averages 20 % of the harvest volume, with VOG Products food loss in Italian apples drops to 6 – 10 % (depending on the year).

“Food waste is not inevitable,” comments Christoph Tappeiner, CEO of VOG Products. “With good organisation and investment in innovation along the supply chain, product losses can be significantly reduced, providing a triple win for producers, consumers and the environment.”

The FAO specifically refers to food loss as “the waste of edible food in the production, post- harvest and processing stages of the food chain”. Besides the wastage of the food itself, food loss also entails environmental costs in the form of loss of land, water, factors of production and labour, and leads to greenhouse gas emissions that contribute to global warming.
For VOG Products, food loss already starts with the company’s mission statement: apples destined for industrial processing are those with minor quality defects (too big, too small or not enough colour) or do not meet the quality standards of fresh fruit, and therefore cannot be sold on the table apples market.

“VOG Products is an international model for minimising harvest and post-harvest losses in the apple supply chain,” remarks Prof. Fischer. “VOG Products also generates significant added value for members in the region by giving them a fair and sustainable payout price.”

Growers who deliver their apples to VOG Products’ members (VOG, VIP, La Trentina and 18 cooperatives) receive an average of 4,000 euro per head or 1,400 euro per hectare for their apples for processing. The producer organisation also creates jobs for around 210 employees. The industrial fruit enhancement strategy pursued in recent years strengthens the region’s high-quality image of table apples, based on a win-win approach that rewards all operators along the supply chain. Generating value for the economy, people and the planet.

A new clinical research paper provides additional evidence that BeniCaros®, a functional food, beverage and supplement ingredient, prepares the immune system and strengthens healthy immune responses, NutriLeads BV announced. The research was recently published in the peer-reviewed journal Nutrients.

The research paper elaborates on previous findings that showed 300 mgs. of BeniCaros accelerated immune responses and significantly reduced the severity and duration of symptoms in a study of 146 healthy human subjects following a controlled challenge with a common cold virus. These latest data demonstrate that BeniCaros, a soluble prebiotic carrot fiber known scientifically as Rhamnogalacturonan-I or cRG-I, significantly reduced individual cold symptoms and helped subjects feel better and maintain their quality of life. The paper is titled, “Effects of Dietary Supplementation with Carrot-Derived Rhamnogalacturonan-I (cRG-I) on Accelerated Protective Immune Responses and Quality of Life in Healthy Volunteers Challenged with Rhinovirus in a Randomized Trial.”

“Subjects taking BeniCaros felt considerably better and reported significant reductions in common cold symptoms, including a runny nose, sore throat, coughing and feeling tired, compared with the placebo group,” said Ruud Albers, Ph.D., NutriLeads founder and Chief Scientific Officer. “The BeniCaros group also reported significantly better quality-of-life scores than the placebo group, including the ability to think clearly, exercise and accomplish daily activities and work inside and outside the home.”

BeniCaros has a dual mode of action that trains the immune system to respond faster, preparing innate immune cells for a heightened state of readiness, and selectively increases beneficial gut microorganisms and their metabolites that support immune responses.

“Our research shows that BeniCaros supports and accelerates healthy immune responses when they are needed most,” said Joana Carneiro, NutriLeads Chief Executive Officer. “These latest data illustrate the ways in which BeniCaros helps individuals live their lives so nothing slows them down.”

Study design

In the randomised, double-blind, placebo-controlled trial, 146 healthy adults were given either BeniCaros or a placebo for eight weeks, after which they were exposed to a standardised dose of a mild rhinovirus via the nose. Researchers utilised blood, fecal and nasal fluid samples to count immune cells, track blood markers, measure immune responses and investigate gene expression. In addition, a validated clinical questionnaire was used to evaluate common cold symptom severity and quality of life.

Subjects were asked to complete the Wisconsin Upper Respiratory Symptom Score-21 (WURSS-21) questionnaire every morning for two weeks starting the day before infection. WURSS-21 is comprised of 21 questions divided into three sections: total score and “how well do you feel today?”, upper respiratory tract infection symptoms, and quality-of-life questions to assess the impact of a common cold on daily activities.

Study results: BeniCaros reduced severity, duration & impact of cold symptoms

Subjects taking 300 mgs. of BeniCaros reported statistically significant reductions in symptom severity (20 – 33 %) and duration (28 – 43 %) compared with the placebo group, based on the total WURSS-21 over 13 days post infection. BeniCaros subjects experienced a lower peak value in severity (day 3) and lower impact (10 – 30 %) of a variety of common cold symptoms, including runny nose, sore throat, cough and feeling tired.

BeniCaros also significantly reduced the negative impact of a common cold on quality of life. In comparison with the placebo group, BeniCaros subjects reported that their colds interfered 10 – 30 % less with their quality of life. Key measurements included the ability to think clearly, walk, climb stairs, exercise, accomplish daily activities, work inside and outside the home and live their personal lives.

Biological study data show BeniCaros supports a cascade of protective immune responses in the presence of a health challenge. BeniCaros accelerated local and systemic immune response biomarkers, including critical anti-viral interferon gene expression and mobilisation of innate immune cells to the site (nasal cavities) of the challenge. Ex vivo stimulation of whole blood samples demonstrated that BeniCaros enhanced the function of natural killer cells, which play an important role in the early innate immune response to virus infections. Importantly, systemic immune responses following BeniCaros supplementation were unchanged in the absence of an immune challenge.

“BeniCaros trains the immune system to be ready to respond when it is challenged,” said Dr. Albers. “It does not lead to broad, non-specific activation of the innate immune system. It is important that immune-support products designed to be taken long term do not stimulate or boost the immune system unnecessarily.”

Euromed’s natural ingredient Pomanox® shows potential to help reduce food intake

According to a recently published clinical study by the department of Dietetics, Nutrition and Biological Sciences, those supplementing with Euromed’s natural extract Pomanox® showed significantly lower levels of hunger and a desire to eat, as well as higher levels of satiety, compared to a placebo group.

In the preliminary, independent, placebo-controlled study conducted at Queen Margaret University, Edinburgh1, twenty-eight healthy subjects were given either three-week supplementation with Pomanox® or a placebo. During week three, satiety parameters were determined on a testing day after participants ingested breakfast and lunch with pomegranate juice (PJ). The results suggest that subjects in the Pomanox® group with the PJ preload were generally more satisfied than those given the placebo. Participants were also less hungry after Pomanox® intake with PJ during the meal than those who consumed placebo juice and capsules. Scores from the visual analogue scales (VAS), which record subjective sensations, showed significantly lower levels of hunger and a desire to eat, as well as higher levels of fullness and satisfaction, thus greater levels of satiety in participants consuming Pomanox® with PJ, compared to the placebo. These participants also liked the smell of the meal significantly more than the placebo group. Interestingly, the consumption of pomegranate extract was associated with a significantly lower amount of food intake during the satiety session compared with the placebo group.

While preliminary, these findings confirm the appetite-regulating effect of polyphenol-rich extracts reported in previous studies, suggesting possible novel new approaches to reducing risk factors for obesity and compulsive eating, and providing more enjoyable meals while dieting.

Andrea Zangara, Scientific Marketing Manager at Euromed, says: “We are very pleased to see these promising results, as they further support the efficacy and safety of Pomanox®, expanding its numerous evidence-based health applications to include weight management and behavioural support. Pomanox® is available in different formats and strengths, and extracted using safe and eco-friendly, water-only technologies (Pure-Hydro Process®) as with all the other ingredients in our line of Mediterranean Fruit and Vegetable Extracts™. Their production is vertically integrated as they originate from selected fruits grown in the Mediterranean region – close to our dedicated manufacturing plant and in accordance with strict and transparent quality control protocols. In summary, they are ideal for inclusion in premium dietary supplements, functional foods and pharmaceuticals.”

Leading spore-forming probiotic BC30TM improves protein absorption from plant sources, a new clinical study has shown.

The findings are significant for food and beverage manufacturers because they demonstrate potential to offer an additional benefit in plant-based products containing BC30. There may be opportunities for products targeting seniors – who typically require higher protein intake to maintain muscle mass – as well as vegetarians, vegans, and athletes.

The double-blind randomised study was carried out over a two-week period, with 30 healthy women between the ages of 50 and 70 taking part. Each consumed a daily plant-based beverage containing 20 g of protein, sourced from a combination of pea and rice proteins, either with or without 1 billion CFUs (colony-forming units) of BC30 (Bacillus coagulans GBI-30, 6086®).

After the final dose, blood samples were analysed for amino acid concentrations. Over the whole course of the measurement period, subjects in the BC30 group showed significantly higher values for total amino acids and total essential amino acids, as well as significantly higher than average levels of certain individual amino acids. The BC30 group also showed also showed higher maximum concentrations of total amino acids, essential amino acids, and several individual amino acids.

Part of Kerry’s ProActive Health Portfolio, BC30 is a patented spore-forming probiotic which can be used in a range of food and beverage products. It is backed by over 25 published papers, including a 2020 study demonstrating that it supports protein absorption from milk protein concentrate.

John Quilter, Kerry VP of Global Portfolio – ProActive Health, said: “Previous research has indicated the potential of BC30 to support protein absorption from plant-based sources, but this is the first human clinical study to do so. We’re now able to say that BC30 supports protein absorption from both dairy and plant sources – it’s another benefit that makes it the leading spore-forming probiotic.”

He added: “One of the reasons this research is so exciting is that it’s in line with so many contemporary food and nutrition trends. With demand for high-protein products firmly in the mainstream, consumers in all groups are interested in foods and beverages that offer efficient protein digestion. At the same time, more and more people are following plant-based diets and looking for sustainable nutrition solutions. Many vegetarians and vegans – along with groups like seniors and athletes – could benefit from more efficient absorption of protein to support outcomes such as muscle-building.”

The study was carried out by researchers at the Exercise and Performance Nutrition Laboratory at the School of Health Sciences at Lindenwood University, Missouri, led by Dr Chad Kerksick, Associate Professor of Exercise Science. A research poster was presented on June 17th, 2022, at the annual conference of the International Society of Sports Nutrition (ISSN). The full study is expected to be published in a scientific journal in late 2022 or early 2023.

About BC30TM
BC30TM (Bacillus coagulans GBI-30, 6086) is a patented, FDA GRAS probiotic ingredient found in more than 1,000 leading food and beverage products around the world. It is a shelf-stable, science-backed probiotic strain that has been shown to support digestive health, immune health, and protein absorption. Unlike most other probiotic strains, BC30 is a spore-former, which makes it highly stable and allows it to remain viable throughout most manufacturing processes and the low pH of stomach acid. Well-researched and easy to formulate into functional food, beverages and companion animal products, BC30 is backed by over 25 published papers. Part of Kerry’s ProActive Health portfolio, BC30 is natural, and available in vegan, non-GMO Project-verified, organic-compliant and allergen-free versions.

The saying ‘an apple a day keeps the doctor away’ is well known but is there any truth in it? There may be according to a major ‘super study’, published in the Journal of the American Heart Association1, which found that not only apples – but orange juice, onions, carrots, broccoli and cabbage – are associated with lower risk of heart disease and stroke.

Scientists at the University of Toronto sifted through more than 80 unique cohort studies which, overall, followed up 4,031,896 individuals for an average of 11 years. During that time, more than 125,000 cardiovascular events e.g. strokes and heart attacks were recorded.

Author, Professor John Sievenpiper, commented: “Public health policies discourage the consumption of certain fruit sources such as 100 % fruit juice, dried fruit, and tropical fruits because of their sugar content and promote vegetables before fruit. However, we found that that different sources of fruit, including 100 % fruit juice, were associated with comparable cardiovascular disease risk reduction as that of vegetables.

“Public health guidance to limit the intake of certain fruit sources because of concerns related to their contribution to sugars may have unintended harm in preventing people from meeting fruit and vegetable targets for cardiovascular disease risk reduction”.

Looking at the detail, the study found that drinking 100 % fruit juice lowered the relative risk of dying from a stroke by 33 percent while eating fruit in general lowered risk by 13 percent. Vegetables cut the risk of stroke deaths by 6 percent. For heart disease mortality, fruit, vegetables and fruit juices were similarly associated with a relative risk reduction of around 13 – 14 percent.

According to the authors, the most important individual fruits and vegetables for lowering the risk of developing cardiovascular disease were citrus fruits, 100 % fruit juices, apples, allium vegetables (garlic, onion, leeks, chives), carrots, cruciferous vegetables (broccoli, cabbage, sprouts) and green leafy vegetables (kale, spinach, watercress).

Professor Sievenpiper concluded: “Higher intakes of fruits and/or vegetables are associated with improvements in all cardiovascular disease outcomes, with fruit associated with the largest risk reductions.

“Greater benefits may be seen for some fruits and vegetables supporting recommendations for emphasizing specific fruit and vegetable sources in dietary guidelines. No fruit and vegetable sources were adversely associated with cardiovascular disease, including fruit sources of concern, such as 100 % fruit juice and dried fruit”.

1Zurbau A et al. (2020) Relation of different fruit and vegetable sources with incident cardiovascular outcomes: A systematic review and meta-analysis of prospective cohort studies. J Am Heart Assoc 9: e017728. DOI: 10.1161/JAHA.120.017728 https://www.ahajournals.org/doi/10.1161/JAHA.120.017728

A new study published by the Centers for Disease Control and Prevention (CDC) found that on average only 12 percent of U.S. adults meet fruit intake and only 10 percent meet vegetable intake recommendations as outlined in the 2020-2025 Dietary Guidelines for Americans (DGA). Low intakes may put Americans at increased risk for chronic diseases such as cardiovascular disease and diabetes.

When looking at this data on the state level,1 the average percentage of adults meeting fruit intake recommendations ranged from 8.4 percent to 16.1 percent, and for vegetables ranged from 5.6 percent to 16.0 percent. The DGAs recommend 1.5 to 2 cup-equivalents of fruit daily for most adults. Although data differed by state, those with Hispanic ethnicity and women were more likely overall to meet fruit intake recommendations.

Low fruit and 100 % fruit juice intake may lead to lower intakes of key nutrients including vitamin C, potassium, and folate, as well as phytonutrients (naturally occurring plant compounds). These nutrients are essential in supporting immune system health and are associated with reduced risk for some chronic conditions. Intake of vitamin C declined 23 percent between 1999 and 2018, driven by decreases in consumption of 100 % fruit juice.2 While whole fruit is recommended, adding just one 8-ounce glass of 100 % orange juice to the daily diet can help fill nutrient and fruit intake gaps while overcoming many of the barriers to fruit intake, including availability, cost, and access. Orange juice and other 100 % fruit juices are readily available year-round and are a cost-effective and convenient way for Americans to move the needle closer to meeting fruit intake recommendations.3

The current analysis by the CDC included data from 294,566 adults aged 18 and older collected as part of the 2019 Behavioral Risk Factor Surveillance system (BRFSS). Data were reported for 49 states and the District of Columbia. Respondents reported their intake per day, week, or month of vegetables and fruit, including 100 % fruit juice, over the previous 30 days.

1Lee et al. MMWR Morb Mortal Wkly Rep. 2022;71(1):1-9
2Brauchla et al. Nutrients. 2021;13(2):420
3Brauchla et al. Public Health Nutrition. 2021; Feb 8;1-7

New study finds that vitamins and bioactives in 100 % orange juice help shore up natural immunity and fight immune-sapping inflammation in the body

A new research review, published in Frontiers in Immunology1, has found that a simple glass of citrus juice – for example orange or grapefruit – contains key nutrients and bioactive substances that help our immune system to work efficiently.

Scientists examined evidence from nearly 200 different studies and reports, and concluded that vitamin C, folate and polyphenol compounds in citrus juices have the capacity to impact on immune health, fight inflammation and improve our defence against bacteria and viruses.

Co-author, Philip Calder, Professor of Nutritional Immunology at Southampton University, said: “A weak immune system increases susceptibility to infections and allows these to become more severe. One component of the immune response is inflammation. Where inflammation is excessive or uncontrolled it can damage body tissues, sometimes irreparably, and affect our ability to fight infections. Having a diet rich in antioxidant foods and drinks is one way to control inflammation and ensure the body can mount an effective immune response. Trials in humans confirm that orange juice consumption reduces inflammation.

“Citrus fruit juices are particularly good sources of vitamin C and folate, which have roles in strengthening the gut and skin barriers which are our first line of defence against viruses and bacteria. In addition, these nutrients – which are absorbed well from fruit juices –support the function of many types of immune cells including phagocytes, natural killer cells, T-cells and B-cells.

“Another area of research is the bioactive polyphenols found in citrus fruit juices which include hesperidin, narirutin and naringin. These not only have anti-inflammatory effects but could also have direct anti-viral effects according to emerging data from modelling studies”.

Dr Carrie Ruxton, from the Fruit Juice Science Centre, comments: “The evidence about the positive role that fruit juices play in the diet continues to build. We know from several large studies that a daily glass of pure fruit juice provides vitamin C, folate and potassium, can help to lower blood pressure, and reduces the risk of stroke. Now it’s clear that citrus juices can also contribute to immune health which is crucial as we all get back to our normal lives”.

1Miles EA & Calder PC (2021) Effects of Citrus Fruit Juices and Their Bioactive Components on Inflammation and Immunity: A Narrative Review. Front. Immunol. 12:712608. https://www.frontiersin.org/articles/10.3389/fimmu.2021.712608/full

Moderate consumption of 100% orange juice should be encouraged in children due to its multiple health benefits and lack of negative impacts on body weight, according to a spate of recent and previous research studies on the topic.

Consuming 100 % orange juice can help supplement the intake of key vitamins, minerals and health-associated bioactive compounds that may be missing in a child’s diet. A growing number of research studies has revealed that children who regularly drink 100 % orange juice have higher intakes of key nutrients, higher quality diets, and may have healthier lifestyle habits, like greater physical activity levels, than children who do not drink OJ.  Plus, recent studies align with past studies which help debunk the myth about 100 % orange juice and weight gain by showing that OJ intake is not associated with weight gain in children.

“Misconceptions about the perceived lack of health benefits of 100 % orange juice are unfortunate and could lead kids to potentially miss out on the nutritional benefits that OJ provides,” said Dr. Rosa Walsh, director of scientific research at the Florida Department of Citrus. “However, study after study confirms that 100 % orange juice not only has a place in the diets of children, but it can also serve as an easy way for parents to provide key nutrients without fear of adverse effect on body weight when served in moderation. By sharing the big picture these results show, we can help correct these misconceptions and empower both consumers and health professionals to make diet decisions grounded in scientific evidence.”

As Americans’ fruit and vegetable consumption continues to erode, particularly among young children, 100 % orange juice could play a key role in providing some of the nutrients kids need. A 4 oz. serving of 100 % orange juice is an excellent source of vitamin C and an 8 oz. serving for older children is a good source of potassium, folate and thiamin while still meaningfully contributing these nutrients at smaller serving sizes. Fortified OJ additionally contributes calcium and vitamin D. Potassium, calcium and vitamin D are considered nutrients of public health concern in the 2020-2025 Dietary Guidelines for Americans.

Research also shows that children who drink 100 % orange juice have higher total fruit consumption, lower intake of added sugar and tend to have higher diet quality and higher physical activity levels compared to those who do not drink OJ.1-4

Further, 100 % orange juice is not being overconsumed by children, despite reports to the contrary. In fact, orange juice consumption by children has declined in recent years along with the amount of key nutrients provided by it. On average, 100 % orange juice accounts for less than 1 % of total daily calorie intake in the diets of children and about 4 % of calories from beverages.2 Children are on average consuming 100 % orange juice well below the 100 % juice limits established by the American Academy of Pediatrics, which supports 4 to 6 ounces for children under age 7 and 8 ounces for older children.

Lastly, consumption of 100 % orange juice is not associated with overweight or obesity in children. In fact, research shows that in some cases, 100 % orange juice consumers had less chance of having elevated body weight and may be taller compared to those who do not consume OJ.1-5 This lack of association between 100 % orange juice intake and body weight is supported by both cross-sectional1-3,6,7 and longitudinal4,5 analyses.

  1. Sakaki et al. Nutrients. 2019;11(11):2687.
  2. Maillot et al. Front Nutr. 2020;7:63.
  3. O’Neil CE et al. Pediatric Research and Child Health. 2020;4(1).
  4. Sakaki JR et al. Public Health Nutr. 2020;1-8.
  5. Sakaki JR et al. Pediatr Obes. 2021;e12781.
  6. O’Neil CE et al. Nutr Res. 2011;31(9):673–682.
  7. Wang Y et al. Public Health Nutr. 2012;15(12):2220-2227.

A new study suggests substituting 100 % fruit juice in the diet in place of beverages containing added sugars may lower health risks for cardiovascular-related disease, including type-2 diabetes and coronary heart disease.

Researchers performed a modeling analysis simulating the substitution of 100 % fruit juices for fruit and sugar-sweetened beverages in more than 34,000 Dutch participants ages 20 to 70. The findings, published in Public Health Nutrition, support previous research and hypotheses suggesting that substituting fruit juice for sugar-sweetened beverages would be associated with lower cardiometabolic risk with no change in risk when fruit juice was substituted for fruit.

When more than three-quarters of sugar-sweetened beverages in the diet were replaced with 100 % fruit juice, researchers found the risk for diabetes was lowered by 17 % when compared to the lowest substitution level of less than one-quarter. A similar substitution analysis found the risk for coronary heart disease was reduced by 12 %. Substituting 100 % fruit juice for whole fruit resulted in no change in risks. These calculations were made while considering other factors such as age, sex, educational level, physical activity, smoking, family history of diabetes, healthy diet index, alcohol, coffee, fruit intake, body mass index, and waist circumference.

“100 % fruit juice is frequently equated to sugar-sweetened beverages because of similar sugar content, but this study suggests their effects on diabetes and heart disease risk could be very different,” said Gail Rampersaud, Florida Department of Citrus registered dietitian nutritionist. “Substituting nutrient dense 100 % orange juice for sugar-sweetened beverages may be quite beneficial toward enhancing the intake of key nutrients, meeting daily fruit recommendations, reducing the intake of added sugars as recommended by the Dietary Guidelines for Americans, and reducing the risks for some health conditions.”

Other research supports findings that the consumption of 100 % orange juice or 100 % fruit juice is not related to risk of metabolic syndrome or diabetes and may have beneficial effects on cardiovascular health. Eight ounces of 100 % orange juice is an excellent source of vitamin C and a good source of potassium, folate, and thiamin. Oranges and 100 % orange juice are the primary dietary sources of the polyphenol, hesperidin, which may have beneficial effects on blood pressure in some individuals.

Current beverage labeling regulations appear to fall short of helping parents identify the ingredients, sugar and juice makeup of beverages they purchase for their children, a recent study published in Pediatric Obesity suggests. This has researchers calling for changes to beverage labeling regulations to increase transparency and help consumers choose healthier beverages.

The experimental online study included over 1,600 parents who had healthy children aged 1 to 5 years old. Parents were shown product label information for commonly consumed children’s beverages, including flavoured waters, 100 % fruit juice, and juice drinks and other beverages containing added sugars or non-nutritive (artificial) sweeteners. Some parents were shown only front labels, while some were shown both front and back or side labels which included the Nutrition Facts panel and other information. Study participants then answered questions concerning the sugar and percent juice content of the beverages.

About one-third of participants indicated they were not confident they could identify the added sugar and juice content of beverages. Only about half of study participants (48 percent) said they looked at the Nutrition Facts panel all or most of the time when choosing beverages for their children.

Overall, participants frequently underestimated the percent of juice in 100 % fruit juice. Even though the percent juice was stated on the package front for the 100 % fruit juice product in the study, only 51 percent of parents who were shown only the package front correctly identified the juice percentage. When exposed to additional information on the back and side panels, 37 percent still could not correctly identify the percent juice and 40 percent incorrectly said that 100 % juice contained added sugars.

Conversely, participants frequently overestimated the amount of pure fruit juice in sugar-sweetened juice drinks and beverages. For an added-sugar product that looks similar to 100 % orange juice but contains only 5 percent juice, almost all participants (98 percent) could not accurately state the amount of pure juice just by looking at the front of the label and, on average, estimated that the product contained 45 percent pure fruit juice, 40 percent higher than the actual juice content. Fewer than half of participants who additionally looked at back/side labels could correctly identify the percent juice content and, on average, estimated that the beverage contained 24 percent pure juice. For beverages that are not 100 % fruit juice there is no requirement to identify sweeteners or juice content on the front label.

“The results are striking and this study suggests that labels for 100 % fruit juice and fruit beverages or drinks are not working as intended and for many parents may result in misunderstandings and confusion when trying to choose healthful beverages for their children,” said Gail Rampersaud, registered dietitian nutritionist in the Scientific Research Department of the Florida Department of Citrus. “Consumers need more education coupled with labels that are clearer and easier to understand,” added Rampersaud.

The results suggest that lack of knowledge and clear labeling may lead parents to choose less healthy added-sugar beverages over 100 % juices, such as 100 % orange juice. The researchers suggest that the Food and Drug Administration allow label declarations that will increase transparency concerning juice percentage and sweetener content, particularly on front of package, to help consumers make healthful beverage choices.

New research shows no adverse association between change in Body Mass Index (BMI) and consumption of 100 % orange juice among older children adding to a growing list of studies suggesting children and teens can benefit from regularly drinking 100 % orange juice without concerns about weight gain. The four-year longitudinal study published in Pediatric Obesity found that drinking 100 % orange juice was associated with smaller changes in BMI over time in girls, with no significant effect on BMI in boys.

The analysis by researchers at the University of Connecticut and Harvard’s School of Public Health and Medical School included children ages 9 to 16 who were followed from 2004 through 2008.1 The analysis showed there was a clear lack of a connection between orange juice and increased BMI in this age group. One hundred percent orange juice contributed, on average, between 40 to 50 calories to the daily diet while milk contributed almost four times that amount, from 150 to 180 calories. This amount of orange juice represents under 4 ounces per day on average, which falls well below the recommendations of the American Academy of Pediatrics, which suggests limits for 100 % fruit juice consumption of 8 oz. daily for children over 7. The 2020-2025 Dietary Guidelines for Americans counts 100 % fruit juice as a fruit serving and recommends that primary beverages either be calorie free – especially water – or contribute beneficial nutrients, such as fat-free and low-fat milk and 100 % fruit juice.2

“Children in this age group fail to consume adequate amounts of fruit and certain micronutrients such as vitamin C and potassium,” said Dr. Rosa Walsh, Director of Scientific Research at the Florida Department of Citrus. “Although the preferred choice is whole fruit, this research supports that moderate consumption of 100 % orange juice can be a beneficial addition to the diet to help meet fruit intake recommendations and is unlikely to contribute to childhood obesity.”

This longitudinal study, funded by an unrestricted grant by the Florida Department of Citrus, adds to the growing body of scientific research supporting the role of 100 % orange juice in adults’ and children’s diets.

  • Another data analysis of nearly 14,000 Americans, ages 4 and older, concluded that people who drink 100% orange juice have lower BMI and healthier lifestyle behaviors than people who don’t drink orange juice.3
  • A longitudinal analysis of more than 7,300 children and adolescents in the GUTSII cohort concluded that 100% fruit juice or OJ intake was not associated with negative effects on body weight, BMI or BMI percentile. In fact, higher OJ intake was associated with greater changes (positive) in height for girls.4
  • A trend analysis for children reported that despite higher energy intakes, there was no significant difference in physical activity levels, percent overweight or obese, or BMI z-score when comparing kids who consume 100 % orange juice versus those who don’t.5
  • A comprehensive review performed by the Academy of Nutrition and Dietetics for their Evidence Analysis Library examined the association between 100 % fruit juice intake and weight in children and concluded that the evidence does not support an association between 100 % fruit juice consumption and weight status or adiposity in children ages 2 to 18 years of age.6

Every glass of 100 % orange juice supports overall health and can help adults and children meet intake recommendations for key nutrients they may be lacking in their diets. An 8-oz. serving size contains vital vitamins and antioxidants, including vitamin C, potassium, folate, hesperidin and more, with no added sugar. From helping improve diet quality to providing key nutrients that can help support a healthy immune system, 100 % orange juice offers a number of health benefits and can also easily be incorporated into simple, great-tasting recipes.

About the Florida Department of Citrus
The Florida Department of Citrus is an executive agency of Florida government charged with the marketing, research and regulation of the Florida citrus industry. Its activities are funded by a tax paid by growers on each box of citrus that moves through commercial channels. The industry employs more than 37,000 people, provides an annual economic impact of $6.5 billion to the state, and contributes hundreds of millions of dollars in tax revenues that help support Florida’s schools, roads and health care services.

1Sakaki JR et al. Pediatric Obesity. 2021;Mar 1:e12781.
2USDA and USDHHS. Dietary Guidelines for Americans, 2020-2025. 9th Edition. December 2020. Available at DietaryGuidelines.gov.
3Wang et al. Pub Health Nutr. 2012;15(12):2220-2227.
4Sakaki et al. Public Health Nutr. 2020 Oct 7;1-8.
5Nicklas et al. International Journal of Child Health and Nutrition. 2020;9(3):100-114.
6Evidence Analysis Library (EAL), Academy of Nutrition and Dietetics. Dietary and Metabolic Impact of Fruit Juice Consumption Evidence Analysis Project.

A new analysis of nutrition research suggests that consumption of 100 % fruit juice, such as 100 % orange juice, by adults may have cardiovascular benefits and does not increase the risk of cardiovascular disease or its risk factors.

The comprehensive analysis, published in the European Journal of Nutrition, pooled and collectively analyzed the results of 21 prospective and 35 randomized clinical studies published through August 2019, and found that drinking moderate amounts of 100 % fruit juice was associated with a lower risk of total cardiovascular events and stroke. The study also reported no association at any level of 100 % fruit juice intake with weight measures, including body weight, body mass index, and waist circumference, and risk for diabetes or risk factors for diabetes such as insulin resistance.1

Based on the analysis by researchers that were part of a working group from the Italian Society of Human Nutrition (SINU), significantly lower risks for total cardiovascular disease were observed at 100 % fruit juice intake levels up to 170 ml per day (between 5 and 6 ounces) and lower risks for stroke were seen at intake amounts up to 200 ml per day (between 6 and 7 ounces). Higher consumption amounts did not significantly increase nor decrease risk. The analysis also found significant reductions in systolic and diastolic blood pressure with 100 % fruit juice consumption, which could have been responsible for the observed risk reduction with cardiovascular events and stroke.

Additionally, no significant associations were seen with 100 % fruit juice intake and increased risk for diabetes or risk factors for diabetes, including blood glucose and insulin levels and measures of insulin sensitivity. Consistent with many other studies, 100 % fruit juice was not associated with weight parameters, including body weight, body mass index, and waist circumference.

A meta-analysis pools together and analyzes the results from previously conducted and published studies. In the hierarchy of research studies, a systematic review/meta-analysis ranks high with regard to the strength and robustness of results.

“These results help further support a positive role for 100 % fruit juice in cardiovascular health without negative effects on weight, risk for diabetes, or risk factors for these major diseases. While the study looked collectively at all 100 % fruit juices we also have research supporting the beneficial effects of 100 % orange juice on some of these very same health outcomes. In the end, a win for 100 % fruit juice is also a win for 100% orange juice,” said Dr. Rosa Walsh, director of scientific research at the Florida Department of Citrus.

This systematic review and meta-analysis, funded through an unrestricted grant by the European Fruit Juice Association (AIJN), adds to the growing body of scientific research supporting the role of 100 % fruit juice and 100 % orange juice in the diet:

  • randomized controlled trial reported that 100 % orange juice reduced systolic blood pressure in adults with pre- or stage-1 hypertension. Hesperidin, provided almost exclusively in the diet by 100 % orange juice and oranges, appears to play a key role in the observed effects.2
  • A meta-analysis of 95 studies showed higher intake of citrus fruit and citrus fruit juice decreased risk of coronary heart disease, cardiovascular disease, stroke, and all-cause mortality. Citrus fruit juices were associated with a 25 percent reduction in the risk for ischemic stroke.3
  • In a systematic review and meta-analysis of prospective cohort studies, 100% fruit juice was associated with a 33 percent lower risk for stroke mortality.4
  • Numerous studies report no association between 100% orange juice or 100% fruit juice intake and body weight in children or adults.5-8

Every glass of 100 % orange juice supports overall health and can help adults and children meet intake recommendations for key nutrients they may be lacking in their diets. An 8-oz. serving size contains vital vitamins and antioxidants, including vitamin C, potassium, folate, hesperidin and more, with no sugar added. From helping improve diet quality to supporting a healthy immune system, 100 % orange juice offers a number of health benefits and can also easily be incorporated into simple, great-tasting recipes.

About the Florida Department of Citrus
The Florida Department of Citrus is an executive agency of Florida government charged with the marketing, research and regulation of the Florida citrus industry.  Its activities are funded by a tax paid by growers on each box of citrus that moves through commercial channels.  The industry employs more than 37,000 people, provides an annual economic impact of $6.5 billion to the state, and contributes hundreds of millions of dollars in tax revenues that help support Florida’s schools, roads and health care services.

References

While whole fruit consumption increased in children between 2003 and 2016, the intake of several important nutrients decreased over time, a new study shows. Adding 100 % orange juice to the diet could help address this shortfall and bolster intake of other key nutrients.

A cross sectional analysis using the nationally representative National Health and Nutrition Examination Survey (NHANES) data on children ages 2 to 18 found significantly higher intakes of whole fruit yet a significant decrease in the intake of folate, riboflavin, thiamin, vitamin C, vitamin D, sodium, potassium, iron and zinc over these time periods.

The FDOC-funded study published in the International Journal of Child Health and Nutrition in July, found that from 2003-2016, the amount of all 100 % fruit juice consumed decreased 44 percent while the percentage of total fruit consumed from whole fruit increased from about 45 percent in 2003 to 65 percent in 2016.

However, the intake of 100 % orange juice (and other 100 % fruit juices) was the likely food source(s) associated with increased consumption of calcium, potassium and phosphorus in certain populations at both time periods (2003 and 2016) and OJ consumers tended to have lower intakes of sugar-sweetened beverages.

The researchers suggest that a possible strategy to decrease inadequate intake of calcium, potassium, and phosphorus is to increase the consumption of 100 % orange juice and other 100 % fruit juice and decrease the consumption of sweetened beverages and coffee/tea.

“Potassium and calcium are under consumed by Americans and have been deemed nutrients of public health concern. These nutrients are important for growing children and 100 % orange juice, particularly calcium-fortified juice, can help enhance the intake of these and other key nutrients,” said Dr. Rosa Walsh, Director of Scientific Research for the Florida Department of Citrus.

Further, vitamin C intake in children has decreased over time and more children have inadequate intake levels. While not linked directly to the decreased consumption of 100 % fruit juice, the results suggest that the increased intake of whole fruit is not adequately addressing vitamin C shortfalls.

Adding 100 % orange juice to the diet, in appropriate amounts as outlined by the American Association of Pediatrics (AAP), can help address the shortfalls or gaps in the intakes of folate, thiamin, vitamin C, potassium and vitamin D in fortified juices. The AAP guidelines suggest limiting portions of 100 % fruit juice to 4 oz. a day for children 1 to 3, 4 to 6 oz. a day for children 4 to 6 and 8 oz. a day for children 7 to 18.

More research is needed to determine the best way to support childhood nutrition. FDOC’s Scientific Research Department has several ongoing projects with researchers to examine the role of 100 % orange juice in the diets of children and adolescents.

Researchers at Western University are studying a molecule found in sweet oranges and tangerines called nobiletin, which they have shown to drastically reduce obesity in mice and reverse its negative side-effects.

But why it works remains a mystery.

New research published in the Journal of Lipid Research demonstrates that mice fed a high-fat, high-cholesterol diet that were also given nobiletin were noticeably leaner and had reduced levels of insulin resistance and blood fats compared to mice that were fed a high-fat, high-cholesterol diet alone.

“We went on to show that we can also intervene with nobiletin,” said Murray Huff, PhD, a Professor at Western’s Schulich School of Medicine & Dentistry who has been studying nobiletin’s effects for over a decade. “We‘ve shown that in mice that already have all the negative symptoms of obesity, we can use nobelitin to reverse those symptoms, and even start to regress plaque build-up in the arteries, known as atherosclerosis.”

But Huff says he and his team at Robarts Research Institute at Western still haven’t been able to pinpoint exactly how nobiletin works. The researchers hypothesized that the molecule was likely acting on the pathway that regulates how fat is handled in the body. Called AMP Kinase, this regulator turns on the machinery in the body that burns fats to create energy, and it also blocks the manufacture of fats.

However, when the researchers studied nobiletin’s effects on mice that had been genetically modified to remove AMP Kinase, the effects were the same.

“This result told us that nobiletin is not acting on AMP Kinase, and is bypassing this major regulator of how fat is used in the body,” said Huff. “What it still leaves us with is the question – how is nobiletin doing this?”

Huff says while the mystery remains, this result is still clinically important because it shows that nobiletin won’t interfere with other drugs that act on the AMP Kinase system. He says current therapeutics for diabetes like metformin for example, work through this pathway.

The next step is to move these studies into humans to determine if nobiletin has the same positive metabolic effects in human trials.

“Obesity and its resulting metabolic syndromes are a huge burden to our health care system, and we have very few interventions that have been shown to work effectively,” said Huff. “We need to continue this emphasis on the discovery of new therapeutics.”

A new study1 published in the Journal of Nutrition and Health Sciences reports that drinking 100 % orange juice following exercise contributes to hydration equally as well as water and sports drinks, positioning the beverage as a viable alternative for post-exercise recovery. The study, conducted by researchers at the University of Kansas and funded by the Florida Department of Citrus, found no differences between 100 % orange juice, sports drinks, or water with respect to taste preference, thirst level, hydration, or gastrointestinal distress following exercise.

Researchers conducted a five-day exercise study with 26 healthy young adults who were moderately trained for endurance exercise. Each day they cycled on a stationary bike for 80 minutes and then consumed approximately eight fluid ounces of commercially available 100 % orange juice, orange-flavored water, or an orange-flavored sports drink. Participants rated the taste of the beverages, thirst levels, and measures of gastrointestinal distress such as reflux or intestinal cramps immediately after the exercise, after drinking the beverages, and after one hour of rest. The researchers measured participants’ hydration status immediately after exercise and after a one-hour rest period.

These findings suggest that 100 % orange juice is a viable post-exercise rehydration strategy, with the beverage receiving positive palatability ratings from study participants when used as a post-exercise rehydration beverage. Additionally, 100 % orange juice was able to satisfy thirst while helping to achieve or maintain hydration following exercise without causing gastrointestinal distress.

“The study showed that people consuming 100 % orange juice were hydrated as well as the participants consuming a sports drink or water. There were no symptoms of serious GI distress with the orange juice despite the carbohydrate content and acidity of the beverage. The results indicate that people can drink orange juice to aid in their rehydration and recovery after exercise,” said Dr. Dawn Emerson, Assistant Professor at the University of Kansas and principal investigator on this study.

An eight-ounce serving of 100 % orange juice provides carbohydrates and is a good source of potassium, an electrolyte, that may provide rehydration and recovery benefits post-exercise. The naturally occurring sugar in 100 % orange juice keeps good company with these and other vitamins, minerals and the antioxidant properties that are all part of the nutrition package 100 % orange juice delivers.

According to the U.S. 2015-2020 Dietary Guidelines for Americans, one cup of 100 % orange juice counts as a fruit serving2 meaning the naturally sweet taste of 100 % orange juice can contribute to an overall healthy diet. Just one-in-ten Americans meet their daily fruit intake as recommended by the Dietary Guidelines, missing out on important nutrients.3 A glass of 100 % orange juice can help close that gap in a convenient, quick way, while also serving as a viable option for post-exercise rehydration.

1Kelly MR, Emerson DM, Landes EJ, Barnes ER, Gallagher PM (2020) Gastrointestinal Implications of Post-Exercise Orange Juice Consumption. J Nutr Health Sci 7(1): 101
2USDA/DHHS. 2015-2020 Dietary Guidelines for Americans. https://health.gov/dietaryguidelines/2015/guidelines
3CDC. Disparities in State-Specific Adult Fruit and Vegetable Consumption. 2015. https://www.cdc.gov/mmwr/volumes/66/wr/mm6645a1.htm?s_cid=mm6645a1_w

A recent study by Wageningen University & Research (WUR), Netherlands, analysed the fate of compostable packaging products in a full- scale industrial organic waste treatment facility. The results show that the tested EN13432 certified products break down within a maximum of 22 days. The project was commissioned by the Dutch Ministry of Economic Affairs and Climate Policy (EZK). “The study shows that the tested objects have the same disintegration and degradation rate as regular biowaste or are even faster. We need more research of this kind, conducted by independent and renowned institutions”, says EUBP Chairman of European Bioplastics (EUBP), François de Bie.

Central aim of the study was to gather more empiric data on the question whether the disintegration rate of compostable products is sufficient to be compatible with the current organic waste treatment practices. In an industrial organic waste treatment trial, a set of nine different compostable plastic products, consisting of organic waste collection bags, plant pots, tea bags, coffee pads, coffee capsules, and fruit labels were tested. “We studied how compostable plastics behave in the current Dutch system for the treatment of GFT (i.e source separated municipal biowaste) and came to the conclusion that compostable products can be processed well with GFT“, says Maarten van der Zee, co-author of the study.

After the first waste treatment cycle of only 11 days, the PLA plant pot already completely disintegrated. “This is significantly faster than paper and most organic matter. Even the orange peel and banana skin (the reference materials) did not completely disintegrate and needed more time” de Bie commented on the study. “The PLA tea bag, which is a typical consumer product, also successfully disintegrated within 22 days.”

The study also analysed the composition of the current visual contamination of conventional plastics in compost, and no compostable plastics were identified amongst the plastics that were found in the compost. “The importance of this result cannot be overstated”, de Bie stresses. “All stakeholders involved in the business of organic recycling, be it waste managers, industry, or legislators, now have the proof that certified compostable plastics actually deliver.”

Read the complete study here: https://bit.ly/2HHAXhn

A study published in the Journal of Nutrition examined the diets of over 36,000 adults in the Netherlands and reports that the intake of pure fruit juice, such as 100 % orange juice, was not associated with a higher risk for type 2 diabetes.

Consumption of any amount of fruit juice, including the highest intake category of eight or more glasses per week, was not associated with an increased risk for type 2 diabetes, according to the study. When the researchers isolated citrus juice intake (orange and grapefruit juice combined), the results were consistent – intake of citrus juices was not associated with an increased risk for diabetes.

This study reinforces the case that fruit juices are not the same as sugar-sweetened beverages (SSBs), particularly with respect to metabolic effects and risk for diabetes. One hundred percent fruit juices have lower glycemic index compared to SSBs and contain beneficial nutrients not found in SSBs, including vitamins, minerals, and bioactive/polyphenolic compounds.

An 8-ounce glass of 100 % orange juice is an excellent source of vitamin C, a good source of potassium, folate, and thiamin, and supplies hesperidin, a polyphenol that has been shown to have health benefits. Orange juice also counts as a fruit serving to help meet fruit intake recommendations.

The study used data from the European Prospective Investigation into Cancer and Nutrition-Netherlands cohort, which began collecting diet and health data in 1993 through 1997 from adults age 20 through 70. The study examined dietary records completed at baseline and categorized fruit juice intake into several intake categories ranging from none to eight or more glasses per week (one glass was considered to be approximately 5 ounces). The study identified 1,477 verified cases of type 2 diabetes over an average 14-year follow up period.

The advantage of this study is that it examined data from a large number of individuals who were followed for a long period of time. However, as a prospective cohort study, data are self-reported, and it cannot show cause and effect. While the analysis took into account important factors that could affect results, such as age, sex, education level, physical activity level, body mass index and overall diet quality, prospective cohort studies are not able to consider each and every factor that could potentially affect results.

Reference:

  • Pure Fruit Juice and Fruit Consumption Are Not Associated with Incidence of Type 2 Diabetes after Adjustment for Overall Dietary Quality in the European Prospective Investigation into Cancer and Nutrition–Netherlands (EPIC-NL) Study
  • Floor R Scheffers, Alet H Wijga, WM Monique Verschuren, Yvonne T van der Schouw, Ivonne Sluijs, Henriëtte A Smit, and Jolanda MA Boer.
  • Journal of Nutrition. 2020 Jan 14. pii: nxz340. doi: 10.1093/jn/nxz340. [Epub ahead of print]

The global apple concentrate market witnessed substantial growth in the past few years, and this growth is expected to continue throughout the forecast period of 2019 – 2029. Towards the end of forecast period, the sales of apple concentrate will translate into revenues exceeding US$ 5 Bn, as per the projections of a new study.

The shelf life of apple concentrate ranges from months to several years, depending on the strength and type of concentrate, as compared to the significantly shorter shelf life of fresh juices. Thus, finished products such as apple juice, sparkling drinks, and soft drinks made from apple concentrate have a longer shelf life than those made from fresh fruit juices.

Longer shelf life of products made from apple concentrate reduces transportation costs and enables manufacturers to export their products and expand their geographical reach. It also allows manufacturers to offer specialized products for the military and astronauts. These products have a longer shelf life than the products made from apple concentrates for civilians.

Key takeaways – Apple concentrate market study

  • Liquid concentrates hold the largest share in the global apple concentrate market by form. Powdered concentrates are expected to witness a slower adoption, owing to its high cost of production.
  • China accounts for the largest share in the global apple concentrate market as it is the largest producer and exporter of apples and apple concentrate offerings in the global market.
  • The beverage industry accounts for the largest share among all segments by application in the apple concentrate market and is expected to grow at the fastest rate during the forecast period.

Manufacturers can gain significant profits from focusing on the B2C channel, which has a limited number of market players.

Apple concentrate market: Competitive landscape

Key players in the global apple concentrate market strive to increase their production capacity by focusing on acquisitions, mergers, and expansion of their own production units. Such investments are also helping manufacturers to expand their geographical reach and penetrate more markets across the globe. Manufacturers are also investing in product innovation and developments for cost-effective processing methods for production of apple concentrate.

For instance, In July 2015, Britvic PLC acquired Empresa Brasileira de Bebidas e Alimentos SA (“ebba”) with an investment of US$ 174.9 Mn.

These insights are based on a report on Apple Concentrate Market by Persistence Market Research.

As one of the only industries that can connect environment at a personal level to the individual, by also talking about health, Food and Beverage brands have an opportunity to drive change through the way they communicate with consumers on these converging topics, to meet this growing and pressing need.

This year’s global research study conducted by Tetra Pak, in partnership with Ipsos, investigates the convergence of health and environment and reveals six new segments of consumers. Each group has unique attitudes around both health and environment, which present clear opportunities for targeted products and messaging for Food and Beverage brands.

Please read and download the full study under https://bit.ly/35ivkAR

A new study suggests higher consumption of sugary beverages, including fruit juice, is associated with increased mortality.

Gavin Partington, director-general of the British Soft Drinks Association, said: “This study is inconclusive, and the way its findings are presented is misleading. All age groups in the UK are falling short on their 5 A Day consumption of fruit and vegetables. Therefore, warning against consuming a small 150 ml portion of pure fruit juice – which counts as one of your 5 A Day – risks people foregoing the vitamin and phytonutrient benefits of fruit juice that this study acknowledges.

“Our research shows adults and teenagers who drink fruit juice are about twice as likely to reach their recommended minimum of 5 A Day, than non-drinkers.”

You can read the highly controversial study “Association of Sugary Beverage Consumption With Mortality Risk in US Adults” under: www.jamanetwork.com

Endothelial cells have an important role in maintaining vascular homeostasis. Age-related disorders (including obesity, diabetes, and hypertension) or aging per se induce endothelial dysfunction that predisposes to the development of atherosclerosis. Polyphenols have been reported to suppress age-related endothelial cell disorders, but their role in vascular function is yet to be determined.

We investigated the influence of boysenberry polyphenol on vascular health under metabolic stress in a murine model of dietary obesity. We found that administration of boysenberry polyphenol suppressed production of reactive oxygen species (ROS) and increased production of nitric oxide (NO) in the aorta. It has been reported that p53 induces cellular senescence and has a crucial role in age-related disorders, including heart failure and diabetes. Administration of boysenberry polyphenol significantly reduced the endothelial p53 level in the aorta and ameliorated endothelial cell dysfunction in iliac arteries under metabolic stress. Boysenberry polyphenol also reduced ROS and p53 levels in cultured human umbilical vein endothelial cells (HUVECs), while increasing NO production. Uncoupled endothelial nitric oxide synthase (eNOS monomer) is known to promote ROS production.

We found that boysenberry polyphenol reduced eNOS monomer levels both in vivo and in vitro, along with an increase of eNOS dimerization. To investigate the components of boysenberry polyphenol mediating these favorable biological effects, we extracted the anthocyanin fractions. We found that anthocyanins contributed to suppression of ROS and p53, in association with increased NO production and eNOS dimerization. In an ex vivo study, anthocyanins promoted relaxation of iliac arteries from mice with dietary obesity. These findings indicate that boysenberry polyphenol and anthocyanins, a major component of this polyphenol, inhibit endothelial dysfunction and contribute to maintenance of vascular homeostasis.

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GfK has carried out a comprehensive analysis of the European retail scene in 32 European countries. The study examines purchasing power, the retail share of private consumption, inflation and sales area productivity, and also includes a turnover prognosis for 2018.

Please download the complete study for free under: https://bit.ly/2vT3cEi

A study released this week illustrates how the European soft drinks industry is rooted in the European economy and boosts progress throughout its value chain. The sector generates € 185 billion revenue – equivalent to 1.24 % of EU GDP, indirectly supports 1.7 million jobs and delivers almost € 30 billion in tax contributions to EU member states.

The industry supports a local value-chain of suppliers, distributors and retailers with a revenue that is 2.5 times greater than that which it receives itself. It contributes revenue, jobs and investment from the agricultural sector where it sources ingredients including fruit, berries and sugar beet; to the packaging and raw materials industries; through to the transport and distribution sectors and finally to the supermarkets, shops, bars and restaurants across the continent where its products are sold.

The study was undertaken by leading drinks industry analysts Global Data to mark UNESDA’s 60th anniversary and is based on 2016 data.

You can access the full report here: www.unesda.eu

This independent human study was the first to examine Meriva® potential on system-level physiology responses during exertional heat stress.

A new double-blind placebo-controlled human studyI reveals that a short-term dietary curcumin-based supplementation may be helpful in the maintenance of the gastrointestinal barrier integrity and physiological strain responses during exertional heat stress. The study has been conducted independently by a team of American researchers at the High Point University (NC).

The study examined an acute supplementation regimen, where participants ingested 5 tablets (500 mg each) of Meriva® curcumin or placebo for three days prior to exertional heat stress (EHS). This dosing strategy was selected with reference to those used in two recent clinical studies demonstrating the positive effects of Meriva® on healthy inflammatory responses to endurance cyclingII and on reducing inflammatory cytokines in circulation.III

EHS was performed in a Darwin chamber (37 °C/25 % RH) where the participants completed 1 hour of treadmill exercise. Before the test, subjects were supplemented with the same daily dose of Meriva®. There were two major findings in this study. First, it demonstrates that dietary curcumin supplementation may reduce the rise in core temperature (Tc), mean body temperature (Tb), Heart Rate (HR) and Physiological Strain Index (PSI) during exertional heat stress. Second, it shows that these changes are accompanied by maintenance in GI barrier integrity and associated cytokine responses, as indicated by the lower circulating concentrations of Intestinal fatty acid binding protein (I- FABP) post-exercise in subjects supplemented with curcumin (58 % vs 87 % in the placebo group, p = 0.002). These data suggest that short-term dietary curcumin supplementation may help to lower EHS risk in non-heat acclimated individuals. This study was the first to examine curcumin for potential benefits on system-level physiology responses during exertional heat stress.

I Szymanski MC et al., Short-term dietary curcumin supplementation reduces gastrointestinal barrier damage and physiological strain responses during exertional heat stress J Appl Physiol, September 2017. Doi:10.1152/japplphysiol.00515.2017.
II Sciberras JN et al., The effect of turmeric (Curcumin) supplementation on cytokine and inflammatory marker responses following 2 hours of endurance cycling. J Int Soc Sports Nutr 12:5, 2015.
III McFarlin BK et al., Reduced inflammatory and muscle damage biomarkers following oral supplementation with bioavailable curcumin. BBA Clin 5:72-78, 2016.

Indena’s Mirtoselect® can improve tear secretion and plasmatic antioxidant potential, as confirmed by Schirmer’s tests value after 4 weeks of supplementation.

A new randomized, double-blinded, placebo-controlled clinical study published in European Review for Medical and Pharmacological Sciences1 highlighted that Mirtoselect®, the Indena proprietary standardized bilberry extract containing 36 % anthocyanins, may have an important role in preserving adequate acqueous levels in people possibly experiencing dry eye conditions.

Aim of the study was to investigate the ability of bilberry extract to maintain adequate tear levels and to confirm its antioxidant potential. 21 healthy subjects experiencing dry eye have been enrolled and randomly assigned to receive Mirtoselect® supplementation (2 tablets corresponding to 160mg) daily or placebo for 4 weeks. The results of Schimer’s test – indicating the volume of tear secretion – before and after the 4-week period showed significant improvements in the mean values for right eye (+71 %, p=0.009) and both eyes (+ 55 % p=0.019) as well as a beneficial tendency for the left eye (+ 43 %, p=0.062) in the supplemented group. In the placebo group, the mean values of Schimer’s test at the end of the treatment were not significant.

“Aged people or those exposed to certain stress conditions for the eye (i.e. dust or dry environment) may experience discomfort, visual disturbance, and tear film instability with potential impairment of the ocular surface”2 – commented Antonella Riva, Product Research Manager at Indena. – “Mirtoselect® is supported by a strong clinical literature, confirming its efficacy profile in the realm of vascular health and ophthalmology. This last study opens a new application for our bilberry extract in subjects with visual fatigue and a higher tendency of dry eye. The observed antioxidant potential is of a great importance due to the fact that a potential relationship between dry eye and relative oxygen species is reported”.

References
1 Riva A. et al, The effect of a natural, standardized bilberry extract (Mirtoselect®) in dry eye: a randomized, double blinded, placebo controlled trial, European Review for Medical and Pharmacological Sciences, 2017; 21: 2518-2525.
2 Dry Eye Workshop (DEWS) DED definition, 2017.