New formulation of award-winning ingredient expands applications into sports and cognition products including RTDs and shots

Nektium has developed a new water-soluble formulation of its award-winning nootropic Zynamite® for cognitive and sports nutrition drinks.

Used to support mental and physical energy, Zynamite^® is a Mangifera indica extract created from sustainably harvested mango leaves. The natural caffeine alternative has been the subject of 10 clinical studies and multiple industry awards since its launch in 2018, earning global recognition for its fast-acting, experiential benefits.

Nektium’s scientists have now created Zynamite^® S to meet growing demand for innovative energy, sports and hydration drinks. It is designed for use in applications such as RTDs and shots where solubility, heat stability and transparency in solution are key.

Zynamite^® S also has a neutral taste and is formulated to enable improved absorption of its bioactive component, mangiferin, which allows for reduced dosages.

Nektium Commercial & Partnership Director Bruno Berheide said: “Excessive caffeine intake is becoming a hot topic and there is high demand for alternatives that deliver instant power and energy that consumers can really feel. Zynamite® stands out as a non-stim energy alternative, naturally enhancing mental and physical energy in a smarter way – and without the side effects of caffeine. Our new Zynamite^® S allows manufacturers the opportunity to formulate innovative beverages that can help consumers ‘get in the zone’ and perform at their best without suffering jitters and anxiety.”

Hybrid drinks

Zynamite^® S can be used alone or in combination with caffeine to provide mental energy and focus as well as supporting physical energy, improved performance and recovery.

It is therefore ideally positioned to tap into the trend for hybrid beverages that blur the lines between energy and sports drinks. Innova Market Insights research shows that of the 56 % of consumers worldwide who regularly use hydration products in conjunction with their exercise routines, more than a third use energy drinks.¹

Bruno Berheide added: “In today’s dynamic functional beverage market, many brands are innovating with hybrid products that offer both mental and physical energy. Zynamite^® S is the perfect option for these products as it delivers clinically backed benefits for mental energy and sports performance within just one hour.”

Clinical benefits

Zynamite^® is supported by a portfolio of safety data and its efficacy has been demonstrated in clinical studies in recognised journals.

Research has shown that, within one hour, a single dose of Zynamite® enhances mental energy and improves performance under fatigued conditions. In addition, it does not increase heart rate or blood pressure, avoiding the side effects associated with caffeine.²

In 2020, Nutrients published a clinical study examining its impact on cognitive performance in adults. It provided evidence that a single dose of Zynamite^® significantly improved cognitive function and performance across a battery of cognitive tasks, including improved focus, improved memory and reduced mental fatigue.³

An independent study in Nutrients in 2024, meanwhile, examined the effects of a single dose of Zynamite^® combined with quercetin on top basketball players in Greece during a basketball exercise stimulation test. Participants in the supplement group were faster, showing a statistically significant improvement in mean circuit lap time compared to those in the placebo group.⁴

¹https://www.innovamarketinsights.com/trends/sports-and-energy-drink-trends/
²López-Ríos, L. et al. ‘Central nervous system activities of extract Mangifera indica L.’ Journal of Ethnopharmacology (2020)
³Wightman, E.L. et al. ‘Acute Effects of a Polyphenol-Rich Leaf Extract of Mangifera indica L. (Zynamite) on Cognitive Function in Healthy Adults: A Double-Blind, Placebo-Controlled Crossover Study’ Nutrients (2020)
⁴Bourdas, D.I. et al. ‘Effects of a Singular Dose of Mangiferin–Quercetin Supplementation on Basketball Performance: A Double-Blind Crossover Study of High-Level Male Players’ Nutrients (2024)

Officially launched and available for purchase online, BRÈINFÚEL (Breinfuel) evolves from coffees, energy drinks, and nootropics to help the brain respond with focus, alertness, and productivity.

Developed by Dr. Gerald Horn, a Lasik surgeon with a background in pharmaceutical science and disruptive drug development, Breinfuel combines highly researched ingredients with an extended release that is designed to support performance and wellbeing.

“Endurance means so many different things to people with various lifestyles, occupations and interests. Yet, the common desired effect is not the jolt offered by traditional caffeinated beverages, but rather sustainable cerebral stamina and high-performance energy,” noted Dr. Horn. “Whether you’re a competitive bodybuilder, a frontline medical worker, or a stay-at-home mom of zoom-schooled children, our mental health is being zapped by today’s challenges and demands. Consumers need a beverage that incorporates more functional benefits that enhance productivity and well-being.”

Breinfuel comes in four palate-pleasing flavours including Thrive Ice, Victory Bliss, Alpha Punch and Limitless Berry. Dr. Horn combined four uniquely differentiated ingredient blends for Breinfuel’s multifaceted effects. The Caffeine Blend, according to Dr. Horn, is “the secret sauce” of Breinfuel, with the best of what’s in coffee without the coffee base. It is derived from green tea and green coffee beans without the toxicity and loss of potency from the roast.

The Fuel Blend includes four grams of low-glycemic sugar, five grams of easily digestible collagen protein, and MCT’s which are a great source of prolonged energy. The Antioxidant blend offers potential added benefits from vitamin C, vitamin E and beet root, all designed to reduce the brain’s known sensitivity to accelerated metabolism. The Brain-Booster blend features zinc, creatine, glycine (from collagen), and L-theanine, all individually shown to support brain health.

“Putting caffeine in water alone can create a toxic jolt to our system, which has contributed to caffeine’s checkered past,” noted Dr. Horn. “Since caffeine is not energy or fuel, but rather a stimulant, it needs to be supported like one. Breinfuel’s attention to these key principles resulted in four targeted blends that, for many, may redefine the caffeine experience.”

The inception of Breinfuel began as part of Dr. Horn’s goal to optimize his nutritional consumption, lifestyle/productivity, and personal health.

“This began as a personal quest to solve the problem of unsupported caffeine in the marketplace, such as in caffeinated drinks with zero calories or high-fructose carbohydrates,” noted Dr. Horn. “Once I and some colleagues began to experience caffeine in a new and better way, I knew it was the right time to bring Breinfuel to market.”

ABOUT BRÈINFÚEL 
Developed by Dr. Gerald Horn, a Lasik surgeon with a background in pharmaceutical science and disruptive drug development, Breinfuel combines highly researched ingredients with an extended release that is designed to support performance and wellbeing. Breinfuel is sold online and comes in four delicious flavours including Thrive Ice, Victory Bliss, Alpha Punch and Limitless Berry. Each bottle of Breinfuel features a proprietary blend of effective ingredients, including: natural caffeine from GCBE and green tea (along with their extracts), D-ribose sugar, collagen protein, MCT’s, vitamin C, vitamin E, beet root, L-theanine, creatine, and zinc.