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Hydro One Premium Beverages, maker of natural functional beverages, announced that its line of US Patent Pending CANABIX® beverages, has been shown to reduce the glycemic indicators, increase insulin production, improve the microbiome and alleviate the symptoms of a pre-clinical model of type 2 diabetes.

CANABIX® is the first and only natural beverage containing a combined formulation of cannabidiol (CBD) and probiotics developed by Hydro One Premium Beverages in 2020. In a study done by researchers at Augusta University, drinking CANABIX instead of water was able to lower Hemoglobin A1c (HbA1c, known as A1c) significantly from 9 % to 5 % in mice with diabetes type 2 (db/db mice). Further, CANABIX increased insulin production in pancreatic cells and altered microbiome towards a protective profile by reducing inflammatory indices. These novel findings were reported as preprint on June 4th 2024 (https://www.biorxiv.org/content/10.1101/2024.06.04.597375v2) and currently is under peer review for publication.

Diabetes is a complex disease involving multiple organs in the body. Therefore, its treatment is challenging because of multi-target tissues, medication complexity, patient adherence to the therapy, and cost, says Dr. Phillip Wang the lead scientist of the research team. Despite significant advances in the treatment of symptoms, the underlying causes of diabetes remain intractable. There have been several studies showing the effects of dietary food and beverage supplements on diabetes. However, to the best of our knowledge this is the first study to report a comprehensive beneficial effect on several major aspects of diabetes by a natural beverage, particularly, lowering HbA1c (from 9 % to 5 %) as well as altering microbiome says corresponding author of the study, Dr. Phillip Wang.

“The gut microbiota plays a central role in immune balance and influences the metabolic processes, crucial factors in the development as well as treatment of type 2 diabetes,” says Dr. Babak Baban, Professor of Immunology at Augusta University and co-author of the study. “Altering the profile of microbiome and the significant reduction in A1c in a few weeks only through a beverage are very significant and exciting cutting-edge achievements that warrant further research and clinical trials,” added Baban.

“We’re thrilled to learn that our CANABIX beverage could potentially have profound beneficial health effects. Since CANABIX is THC free, we have many athletes and doctors who already use it and have no issues with blood or urine tests,” says Sammy Nasrollahi, the CEO of Hydro One Beverages, “These are very promising outcomes resulting from pre-clinical studies conducted by a scientific team at Augusta University. As the central core of our mission, we are committed to continue working with the scientific community to promote a higher quality healthier lifestyle by expanding our effective and affordable solutions to those managing prediabetes and diabetes.”

CANABIX comes in three flavours: lemon cucumber, dragon fruit and peach tea. CANABIX the first and only beverage containing 30 mg of CBD and probiotics. A limited number of CANABIX samples are currently available for purchase through Hydro One Beverages by contacting Sammy Nasrollahi at snasrollahi@hydroonebeverages.com.

Disclosure: Dr. Babak Baban is affiliated with Hydro One beverages.

The KHS Group and Ferrum AG are intensifying their longstanding cooperation. Pending approval from antitrust authorities, KHS GmbH will be acquiring a stake in Ferrum Packaging AG. The aim is to optimally bundle the competencies of both machine-engineering companies to form a common system portfolio in the interest of providing integrated customer systems. At the same time, customers will also benefit in the future from well thought-out, one stop-shop services.

The KHS Group and Ferrum AG have been working together extremely successfully in the can segment for years. Dortmund full-service provider KHS values most of all its Swiss partner’s innovative machine technology and its expertise based on many years of experience, emphasizes Martin Resch, CFO in charge of purchasing at KHS. “Ferrum AG is the worldwide well-known manufacturer of can seamers. Combined with our future-oriented solutions in the field of filling and packaging technology, we form an effective union that is valued highly in the market.”

The two engineering companies are now intensifying their cooperation even further. Ferrum Packaging AG was founded as a subsidiary of Ferrum AG and incorporates Ferrum’s entire worldwide can seaming business. KHS will be acquiring minority ownership in Ferrum. At the same time, Ferrum Packaging Inc., the US subsidiary of Ferrum Packaging AG, will be taking over KHS’ can seaming business together with its employees and will be integrating it into the joint offer.

Intelligently combined system solutions

The aim of the merger is to develop and globally market joint solutions. To date, the KHS Group has offered tried and tested Ferrum can seamers only as accessory components for its canning lines. Effective immediately, work in close cooperation will begin on developing even more efficient systems including a filler-seamer block. “Based on skilled future planning of technical components, block solutions are to be designed to be as integrative as possible and do away with redundant functions,” says Dr. Siegmar Stang, Executive Vice President Wet Area at KHS.

Combined filler-seamers designed for the maximum capacity class are planned with clear benefits for the overall process, as Oliver Bühler, CTO of Ferrum Packaging AG, explains. “We don’t want to merely present one solution; we want to develop a comprehensive system portfolio that meets the needs of every customer while offering clear customer benefits.” Among other things, the two partners have set themselves as targets for their new developments a lower TCO1 through shorter changeover times and more rapid sanitizing phases. In addition, the hygienic environment of the systems is to be further optimized.

Comprehensive one-stop-shop services

The intensified cooperation will also bring about extensive customer benefits in the area of customer service. In the future, all services for combined systems from KHS and Ferrum will be offered from a single source. “This will not only reduce the effort for our customers, they will also benefit from shorter machine wait and downtimes,” explains Dr. Beat Bühlmann, President of the Board of Directors at Ferrum.

The planned services include joint overhauls of the systems and integration of the KHS remote maintenance system ReDiS2. Coordinating the supply of spare parts will also result in improvements in discontinuation management to ensure continued operation of the machines and thus the availability of systems.

1 TCO = Total Cost of Ownership
2 ReDiS = Remote Diagnostic Service