New Research Evidences Amla Fruit's Powerful Health Benefits
Taiyo is bringing the long heritage of ayurvedic medicine to a scientifically researched, functional ingredient that is suited to a wide range of food, beverage and supplement applications. New clinical research published in the British Journal of Nutrition[i] provides a scientific mechanistic basis for the traditional use of the amla fruit in anti-inflammatory and anticoagulant activity.
For the first time, the research evaluates the potential use of SunAmla™ amla fruit extract for the treatment or prevention of cardiovascular disorder. Poor endothelial cell function has been linked to hypertension, arterial and venous thrombosis, and artherosclerosis. The effects of amla fruit extract were measured in vitro on lipopolysaccharide (LPS)-induced tissue factor expression in human umbilical endothelial cells. In addition, a LPS-induced endotoxaemia rat model was used to evaluate the anti-inflammatory effects of amla fruit extract in vivo.
The amla fruit extract significantly reduced LPS-induced tissue factor expression and, in a leucocyte adhesion model of inflammation, significantly decreased LPS-induced adhesion of human monocytic cells to human umbilical vein endothelial cells. In the LPS-induced endotoxaemia rat model, oral administration of amla fruit extract significantly decreased concentrations of pro-inflammatory cytokines compared with the control group. The combined anti-inflammatory and anticoagulant activities of amla may help prevent and treat a variety of vascular disorders including thrombosis and poor blood pressure.
In Ayurveda, amla is a potent rasayana[ii] for the treatment and prevention of inflammatory disease. Metabolic, digestive and immune functions also benefit from the amla’s natural properties. SunAmla offers a powerful combination of nutrients including vitamin C, polyphenols gallic acid and ellagic acid, minerals, fibres, proteins and amino acids, and complex structured tannins recognised for their antioxidant[iii], anti-carcinogenic[iv], cytoprotective[v], anti-diabetic[vi] and antimicrobial[vii] properties.
Josef Skrna, managing director at Taiyo GmbH said: “SunAmla is supplied in a highly bioavailable form to facilitate the delivery of vital components. This natural amla fruit extract is ideal for manufacturers looking to develop products to support cardiovascular health, as well as digestive and immune health and general wellbeing.”
SunAmla is a water soluble powder produced by mild water extraction, without the use of solvents, and is GMO and gluten-free. It is approved for use in dietary supplements in Europe. SunAmla’s pleasant fruit taste is well suited to dietary supplements and a wide range of foods including nutritional bars, ready-to-mix beverages, cereals, yoghurts, jams and ice cream. Products from Taiyo’s portfolio are available throughout Europe via Taiyo GmbH, the European subsidiary of Taiyo Kagaku.
[i] Theertham Pradyumna Rao, Takayuki Okamoto, Nobuyuki Akita, Tatsuya Hayashi, Naomi Kato-Yasuda and Koji Suzuki. Amla (Emblica officinalis Gaertn.) extract inhibits lipopolysaccharide-induced procoagulant and pro-inflammatory factors in cultured vascular endothelial cells. British Journal of Nutrition, CJO2013. doi:10.1017/S0007114513001669.
[ii] Path (āyana) of essence (rasa). The science of macrobiotics or lengthening lifespan in ayurvedic medicine.
[iii] Rao TP, Sakaguchi N, Juneja LR, et al. (2005) Amla (Embica officianalis Gaertn.) extracts reduce oxidative stress in streptozotocin-induced diabetic rats. J Med Food 8, 362–368.
[iv] Baliga MS & Dsouza JJ (2011) Amla (Emblica officinalis Gaertn.), a wonder berry in the treatment and prevention of cancer. Eur J Cancer Prev 20, 225–239.
[v] Reddy VD, Padmavathi P, Gopi S, et al. (2010) Protective effect of Emblica officinalis against alcohol-induced hepatic injury by ameliorating oxidative stress in rats. Indian J Clin Biochem 25, 419–424.
[vi] Akhtar MS, Ramzan A, Ali A, et al. (2011) Effect of Amla fruit (Emblica officinalis Gaertn.) on blood glucose and lipid profile of normal subjects and type 2 diabetic patients. Int J Food Sci Nutr 62, 609–616.
[vii] Saeed S & Tariq P (2007) Antibacterial activities of Emblica officinalis and Corandrum stivum against gram negative urinary pathogens. Pak J Pharm Sci 20, 32–35.
Taiyo GmbH is the European office of Taiyo Kagaku Japan, a leading manufacturer of functional ingredients for the food, beverage and dietary supplements industries. Taiyo focuses on developing scientifically-researched ingredients derived from natural sources to strengthen the body’s ability to preserve health and well-being.
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